Idiopathic normal pressure hydrocephalus

Idiopathic normal pressure hydrocephalus (INPH) is a neurodegenerative disease which affects the elderly, with a significant prevalence in the general population (0,2% - 5,9%), thus a common pathology encountered by neurologists and neurosurgeons, alike. Although the widespread availability of moder...

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Main Authors: D. Adam, D. Iftimie, Cristiana Moisescu
Format: Article
Language:English
Published: London Academic Publishing 2019-09-01
Series:Romanian Neurosurgery
Subjects:
Online Access:https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/1178
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author D. Adam
D. Iftimie
Cristiana Moisescu
author_facet D. Adam
D. Iftimie
Cristiana Moisescu
author_sort D. Adam
collection DOAJ
description Idiopathic normal pressure hydrocephalus (INPH) is a neurodegenerative disease which affects the elderly, with a significant prevalence in the general population (0,2% - 5,9%), thus a common pathology encountered by neurologists and neurosurgeons, alike. Although the widespread availability of modern imaging techniques has facilitated the diagnosis of this disorder, the clinical manifestations can often be misleading. Also, an overlap with other degenerative or psychiatric diseases can make the differential diagnosis even more challenging. Cerebrospinal fluid (CSF) diversion procedures are the first line of treatment for INPH. Nowadays, there are several shunting options available, including: ventriculoperitoneal (the most commonly used), ventriculoatrial, ventriculopleural, ventriculosternal, lumboperitoneal, endoscopic third ventriculostomy. Choosing a procedure tailored to the individual patient is essential for therapeutic success. Although they are generally straightforward surgical interventions, they associate a high rate of failure, regardless of procedure used, which emphasizes the need for regular clinical and imagistic follow-up. Thus, INPH remains a disease where there is significant room for improvement, both in diagnosis and treatment.
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spelling doaj.art-79a1bfec1d174a298cd6ec7fe1c1a3172022-12-22T01:42:26ZengLondon Academic PublishingRomanian Neurosurgery1220-88412344-49592019-09-0133310.33962/roneuro-2019-045Idiopathic normal pressure hydrocephalusD. AdamD. IftimieCristiana MoisescuIdiopathic normal pressure hydrocephalus (INPH) is a neurodegenerative disease which affects the elderly, with a significant prevalence in the general population (0,2% - 5,9%), thus a common pathology encountered by neurologists and neurosurgeons, alike. Although the widespread availability of modern imaging techniques has facilitated the diagnosis of this disorder, the clinical manifestations can often be misleading. Also, an overlap with other degenerative or psychiatric diseases can make the differential diagnosis even more challenging. Cerebrospinal fluid (CSF) diversion procedures are the first line of treatment for INPH. Nowadays, there are several shunting options available, including: ventriculoperitoneal (the most commonly used), ventriculoatrial, ventriculopleural, ventriculosternal, lumboperitoneal, endoscopic third ventriculostomy. Choosing a procedure tailored to the individual patient is essential for therapeutic success. Although they are generally straightforward surgical interventions, they associate a high rate of failure, regardless of procedure used, which emphasizes the need for regular clinical and imagistic follow-up. Thus, INPH remains a disease where there is significant room for improvement, both in diagnosis and treatment.https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/1178idiopathic normal pressurehydrocephalusCSF shunting
spellingShingle D. Adam
D. Iftimie
Cristiana Moisescu
Idiopathic normal pressure hydrocephalus
Romanian Neurosurgery
idiopathic normal pressure
hydrocephalus
CSF shunting
title Idiopathic normal pressure hydrocephalus
title_full Idiopathic normal pressure hydrocephalus
title_fullStr Idiopathic normal pressure hydrocephalus
title_full_unstemmed Idiopathic normal pressure hydrocephalus
title_short Idiopathic normal pressure hydrocephalus
title_sort idiopathic normal pressure hydrocephalus
topic idiopathic normal pressure
hydrocephalus
CSF shunting
url https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/1178
work_keys_str_mv AT dadam idiopathicnormalpressurehydrocephalus
AT diftimie idiopathicnormalpressurehydrocephalus
AT cristianamoisescu idiopathicnormalpressurehydrocephalus