Characterization of Immunogenic and Protective Properties of the Modified Variants of the Strain Francisella tularensis 15 NIIEG

Characterization of Immunogenic and Protective Properties of the Modified Variants of the Strain Francisella tularensis 15 NIIEG

Francisella tularensis is an intracellular bacterium that causes tularemia. Progress in creating a safe and effective vaccine for the prevention of tularemia is challenging due to a lack of knowledge about immunological parameters indicative of protective adaptive immunity. Objective of the research...

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Bibliographic Details
Main Authors: A. S. Kartseva, O. V. Kalmantaeva, M. V. Silkina, T. I. Kombarova, V. M. Pavlov, A. N. Mokrievich, V. V. Firstova
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2020-10-01
Series:Проблемы особо опасных инфекций
Subjects:
tularemia
vaccine
t-lymphocytes
cytokines
b-lymphocytes
protectivity
Online Access:https://journal.microbe.ru/jour/article/view/1365

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