Porous tantalum scaffolds: Fabrication, structure, properties, and orthopedic applications
Porous tantalum scaffolds have been developed and clinically utilized as superior implantable biomaterials for orthopedic applications owing to their exceptional corrosion resistance, biocompatibility, osteointegration, and osteoconductivity. Moreover, the biomimetic porous structure and mechanical...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-11-01
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| Series: | Materials & Design |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S026412752100650X |
| _version_ | 1818690417688838144 |
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| author | Hairui Gao Jingzhou Yang Xia Jin Xinhua Qu Faqiang Zhang Dachen Zhang Haishen Chen Huiling Wei Shupei Zhang Weitao Jia Bing Yue Xiaopeng Li |
| author_facet | Hairui Gao Jingzhou Yang Xia Jin Xinhua Qu Faqiang Zhang Dachen Zhang Haishen Chen Huiling Wei Shupei Zhang Weitao Jia Bing Yue Xiaopeng Li |
| author_sort | Hairui Gao |
| collection | DOAJ |
| description | Porous tantalum scaffolds have been developed and clinically utilized as superior implantable biomaterials for orthopedic applications owing to their exceptional corrosion resistance, biocompatibility, osteointegration, and osteoconductivity. Moreover, the biomimetic porous structure and mechanical properties of these scaffolds match those of human bone tissues. Over the past twenty years, the fabrication, structure and properties optimization, and application expansion of porous tantalum scaffolds have been advanced by emerging manufacturing technologies, characterization methodologies, and clinical utilization strategies. Combining our innovative work and over two hundred extant publications, we overview the fabrication, structure, properties, and orthopedic applications of porous tantalum bone scaffolds. Additive manufacturing has become a powerful and versatile technique for fabricating patient-specific and anatomy-matching porous tantalum bone implants with well-designed architectures. Additively manufactured tantalum scaffolds are deemed as new biomaterials for bone repair, as their microstructures and mechanical properties differ from those of bioimplants fabricated by traditional technologies. To understand the safety and effectiveness of these scaffolds for orthopedic applications, we must undertake basic scientific investigations, in vitro studies, pre-clinical studies, and clinical research. Biomechanical studies and porous structure design based on finite element analysis are additional hot topics in tantalum scaffold research. |
| first_indexed | 2024-12-17T12:25:40Z |
| format | Article |
| id | doaj.art-79a5aacc191a48da855d3b5e3966fb3f |
| institution | Directory Open Access Journal |
| issn | 0264-1275 |
| language | English |
| last_indexed | 2024-12-17T12:25:40Z |
| publishDate | 2021-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials & Design |
| spelling | doaj.art-79a5aacc191a48da855d3b5e3966fb3f2022-12-21T21:48:47ZengElsevierMaterials & Design0264-12752021-11-01210110095Porous tantalum scaffolds: Fabrication, structure, properties, and orthopedic applicationsHairui Gao0Jingzhou Yang1Xia Jin2Xinhua Qu3Faqiang Zhang4Dachen Zhang5Haishen Chen6Huiling Wei7Shupei Zhang8Weitao Jia9Bing Yue10Xiaopeng Li11School of Mechanical & Automobile Engineering, Qingdao University of Technology, Qingdao, Shandong, PR ChinaSchool of Mechanical & Automobile Engineering, Qingdao University of Technology, Qingdao, Shandong, PR China; Shenzhen Dazhou Medical Technology Co., Ltd., Shenzhen, Guangdong, PR China; Center of Biomedical Materials 3D Printing, National Engineering Laboratory for Polymer Complex Structure Additive Manufacturing, Baoding, Hebei, PR China; Corresponding authors at: School of Mechanical & Automobile Engineering, Qingdao University of Technology, Qingdao, Shandong, PR China (J. Yang).School of Mechanical & Automobile Engineering, Qingdao University of Technology, Qingdao, Shandong, PR China; Key Lab of Industrial Fluid Energy Conservation and Pollution Control, Ministry of Education, Qingdao, Shandong, PR ChinaDepartment of Orthopaedics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, PR ChinaSchool of Mechanical & Automobile Engineering, Qingdao University of Technology, Qingdao, Shandong, PR ChinaShenzhen Dazhou Medical Technology Co., Ltd., Shenzhen, Guangdong, PR China; Center of Biomedical Materials 3D Printing, National Engineering Laboratory for Polymer Complex Structure Additive Manufacturing, Baoding, Hebei, PR ChinaShenzhen Dazhou Medical Technology Co., Ltd., Shenzhen, Guangdong, PR China; Center of Biomedical Materials 3D Printing, National Engineering Laboratory for Polymer Complex Structure Additive Manufacturing, Baoding, Hebei, PR ChinaShenzhen Dazhou Medical Technology Co., Ltd., Shenzhen, Guangdong, PR China; Center of Biomedical Materials 3D Printing, National Engineering Laboratory for Polymer Complex Structure Additive Manufacturing, Baoding, Hebei, PR ChinaShenzhen Dazhou Medical Technology Co., Ltd., Shenzhen, Guangdong, PR China; Center of Biomedical Materials 3D Printing, National Engineering Laboratory for Polymer Complex Structure Additive Manufacturing, Baoding, Hebei, PR ChinaDepartment of Orthopedic Surgery, Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai, PR China; Corresponding authors at: School of Mechanical & Automobile Engineering, Qingdao University of Technology, Qingdao, Shandong, PR China (J. Yang).Department of Orthopaedics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, PR China; Corresponding authors at: School of Mechanical & Automobile Engineering, Qingdao University of Technology, Qingdao, Shandong, PR China (J. Yang).School of Mechanical and Manufacturing Engineering, University of New South Wales (UNSW Sydney), Sydney, NSW 2052, Australia; Corresponding authors at: School of Mechanical & Automobile Engineering, Qingdao University of Technology, Qingdao, Shandong, PR China (J. Yang).Porous tantalum scaffolds have been developed and clinically utilized as superior implantable biomaterials for orthopedic applications owing to their exceptional corrosion resistance, biocompatibility, osteointegration, and osteoconductivity. Moreover, the biomimetic porous structure and mechanical properties of these scaffolds match those of human bone tissues. Over the past twenty years, the fabrication, structure and properties optimization, and application expansion of porous tantalum scaffolds have been advanced by emerging manufacturing technologies, characterization methodologies, and clinical utilization strategies. Combining our innovative work and over two hundred extant publications, we overview the fabrication, structure, properties, and orthopedic applications of porous tantalum bone scaffolds. Additive manufacturing has become a powerful and versatile technique for fabricating patient-specific and anatomy-matching porous tantalum bone implants with well-designed architectures. Additively manufactured tantalum scaffolds are deemed as new biomaterials for bone repair, as their microstructures and mechanical properties differ from those of bioimplants fabricated by traditional technologies. To understand the safety and effectiveness of these scaffolds for orthopedic applications, we must undertake basic scientific investigations, in vitro studies, pre-clinical studies, and clinical research. Biomechanical studies and porous structure design based on finite element analysis are additional hot topics in tantalum scaffold research.http://www.sciencedirect.com/science/article/pii/S026412752100650XTantalum scaffoldsOrthopedic implantBone reconstructionAdditive manufacturingPore structure |
| spellingShingle | Hairui Gao Jingzhou Yang Xia Jin Xinhua Qu Faqiang Zhang Dachen Zhang Haishen Chen Huiling Wei Shupei Zhang Weitao Jia Bing Yue Xiaopeng Li Porous tantalum scaffolds: Fabrication, structure, properties, and orthopedic applications Materials & Design Tantalum scaffolds Orthopedic implant Bone reconstruction Additive manufacturing Pore structure |
| title | Porous tantalum scaffolds: Fabrication, structure, properties, and orthopedic applications |
| title_full | Porous tantalum scaffolds: Fabrication, structure, properties, and orthopedic applications |
| title_fullStr | Porous tantalum scaffolds: Fabrication, structure, properties, and orthopedic applications |
| title_full_unstemmed | Porous tantalum scaffolds: Fabrication, structure, properties, and orthopedic applications |
| title_short | Porous tantalum scaffolds: Fabrication, structure, properties, and orthopedic applications |
| title_sort | porous tantalum scaffolds fabrication structure properties and orthopedic applications |
| topic | Tantalum scaffolds Orthopedic implant Bone reconstruction Additive manufacturing Pore structure |
| url | http://www.sciencedirect.com/science/article/pii/S026412752100650X |
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