A modular platform for one-step assembly of multi-component membrane systems by fusion of charged proteoliposomes

Assembling multiple biological components into synthetic lipid vesicles is a limiting step in the manufacture of biomimetic cell-like structures. Here the authors use fusogenic proteoliposomes of opposite charge for fast assembly of a minimal electron transport chain consisting of F1F0 ATP-synthase...

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Main Authors: Robert R. Ishmukhametov, Aidan N. Russell, Richard M. Berry
Format: Article
Language:English
Published: Nature Portfolio 2016-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13025
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author Robert R. Ishmukhametov
Aidan N. Russell
Richard M. Berry
author_facet Robert R. Ishmukhametov
Aidan N. Russell
Richard M. Berry
author_sort Robert R. Ishmukhametov
collection DOAJ
description Assembling multiple biological components into synthetic lipid vesicles is a limiting step in the manufacture of biomimetic cell-like structures. Here the authors use fusogenic proteoliposomes of opposite charge for fast assembly of a minimal electron transport chain consisting of F1F0 ATP-synthase and the proton pump bo3-oxidase.
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spelling doaj.art-79ab5c276ed346169bc8cceb064fb0992022-12-21T19:32:59ZengNature PortfolioNature Communications2041-17232016-10-017111010.1038/ncomms13025A modular platform for one-step assembly of multi-component membrane systems by fusion of charged proteoliposomesRobert R. Ishmukhametov0Aidan N. Russell1Richard M. Berry2Department of Physics, University of Oxford, Clarendon LaboratoryDepartment of Physics, University of Oxford, Clarendon LaboratoryDepartment of Physics, University of Oxford, Clarendon LaboratoryAssembling multiple biological components into synthetic lipid vesicles is a limiting step in the manufacture of biomimetic cell-like structures. Here the authors use fusogenic proteoliposomes of opposite charge for fast assembly of a minimal electron transport chain consisting of F1F0 ATP-synthase and the proton pump bo3-oxidase.https://doi.org/10.1038/ncomms13025
spellingShingle Robert R. Ishmukhametov
Aidan N. Russell
Richard M. Berry
A modular platform for one-step assembly of multi-component membrane systems by fusion of charged proteoliposomes
Nature Communications
title A modular platform for one-step assembly of multi-component membrane systems by fusion of charged proteoliposomes
title_full A modular platform for one-step assembly of multi-component membrane systems by fusion of charged proteoliposomes
title_fullStr A modular platform for one-step assembly of multi-component membrane systems by fusion of charged proteoliposomes
title_full_unstemmed A modular platform for one-step assembly of multi-component membrane systems by fusion of charged proteoliposomes
title_short A modular platform for one-step assembly of multi-component membrane systems by fusion of charged proteoliposomes
title_sort modular platform for one step assembly of multi component membrane systems by fusion of charged proteoliposomes
url https://doi.org/10.1038/ncomms13025
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