Age and Primary Vaccination Background Influence the Plasma Cell Response to Pertussis Booster Vaccination

Age and Primary Vaccination Background Influence the Plasma Cell Response to Pertussis Booster Vaccination

Pertussis is a vaccine-preventable disease caused by the bacterium <i>Bordetella pertussis</i>. Over the past years, the incidence and mortality of pertussis increased significantly. A possible cause is the switch from whole-cell to acellular pertussis vaccines, although other factors ma...

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Bibliographic Details
Main Authors: Annieck M. Diks, Pauline Versteegen, Cristina Teodosio, Rick J. Groenland, Bas de Mooij, Anne-Marie Buisman, Alba Torres-Valle, Martín Pérez-Andrés, Alberto Orfao, Guy A. M. Berbers, Jacques J. M. van Dongen, Magdalena A. Berkowska, on behalf of the IMI-2 PERISCOPE Consortium
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Vaccines
Subjects:
Tdap
flow cytometry
acellular pertussis vaccine (aP)
whole-cell pertussis vaccine (wP)
plasma cells
ELISpot
Online Access:https://www.mdpi.com/2076-393X/10/2/136

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