Up-front mutation detection in circulating tumor DNA by droplet digital PCR has added diagnostic value in lung cancer

Up-front mutation detection in circulating tumor DNA by droplet digital PCR has added diagnostic value in lung cancer

Identification of actionable mutations in advanced stage non-squamous non-small-cell lung cancer (NSCLC) patients is recommended by guidelines as it enables treatment with targeted therapies. In current practice, mutations are identified by next-generation sequencing of tumor DNA (tDNA-NGS), which r...

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Bibliographic Details
Main Authors: Esther Visser, Remco de Kock, Sylvia Genet, Ben van den Borne, Maggy Youssef-El Soud, Huub Belderbos, Gerben Stege, Marleen de Saegher, Susan van ’t Westeinde, Maarten Broeren, Federica Eduati, Birgit Deiman, Volkher Scharnhorst
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Translational Oncology
Subjects:
Liquid biopsy
Droplet-digital PCR
NSCLC
Mutation analysis
Circulating tumor DNA
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523322002480

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