Fibronectin mediates activin A-promoted human trophoblast migration and acquisition of endothelial-like phenotype

Fibronectin mediates activin A-promoted human trophoblast migration and acquisition of endothelial-like phenotype

Abstract Background During human early placentation, a proportion of extravillous trophoblasts (EVTs) migrate to the maternal decidua, differentiating into endovascular EVTs to remodel spiral arteries and ensure the establishment of blood circulation at the maternal-fetal interface. Inadequate EVT m...

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Bibliographic Details
Main Authors: Xiangxin Lan, Ling Guo, Cuiping Hu, Qian Zhang, Jianye Deng, Yufeng Wang, Zi-Jiang Chen, Junhao Yan, Yan Li
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
Activin A
Fibronectin
Trophoblast
Migration
Endothelial-like tube formation
Pregnancy
Online Access:https://doi.org/10.1186/s12964-023-01463-z

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