Ectopic expression of human TUBB8 leads to increased aneuploidy in mouse oocytes
Abstract Aneuploidy seriously compromises female fertility and increases incidence of birth defects. Rates of aneuploidy in human eggs from even young women are significantly higher than those in other mammals. However, intrinsic genetic factors underlying this high incidence of aneuploidy in human...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2023-10-01
|
| Series: | Cell Discovery |
| Online Access: | https://doi.org/10.1038/s41421-023-00599-z |