Hepatitis B Vaccination in Senegalese Children: Coverage, Timeliness, and Sociodemographic Determinants of Non-Adherence to Immunisation Schedules (ANRS 12356 AmBASS Survey)
Detailed knowledge about hepatitis B virus (HBV) vaccination coverage and timeliness for sub-Saharan Africa is scarce. We used data from a community-based cross-sectional survey conducted in 2018–2019 in the area of Niakhar, Senegal, to estimate coverage, timeliness, and factors associated with non-...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/9/5/510 |
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| author | Lauren Périères Fabienne Marcellin Gora Lo Camelia Protopopescu El Hadji Ba Marion Coste Coumba Touré Kane Gwenaëlle Maradan Aldiouma Diallo Cheikh Sokhna Sylvie Boyer on behalf of the ANRS 12356 AmBASS Survey Study Group |
| author_facet | Lauren Périères Fabienne Marcellin Gora Lo Camelia Protopopescu El Hadji Ba Marion Coste Coumba Touré Kane Gwenaëlle Maradan Aldiouma Diallo Cheikh Sokhna Sylvie Boyer on behalf of the ANRS 12356 AmBASS Survey Study Group |
| author_sort | Lauren Périères |
| collection | DOAJ |
| description | Detailed knowledge about hepatitis B virus (HBV) vaccination coverage and timeliness for sub-Saharan Africa is scarce. We used data from a community-based cross-sectional survey conducted in 2018–2019 in the area of Niakhar, Senegal, to estimate coverage, timeliness, and factors associated with non-adherence to the World Health Organisation-recommended vaccination schedules in children born in 2016 (year of the birth dose (BD) introduction in Senegal) and 2017–2018. Vaccination status was assessed from vaccination cards, surveillance data, and healthcare post vaccination records. Among 241 children with available data, for 2016 and 2017–2018, respectively, 31.0% and 66.8% received the BD within 24 h of birth (BD schedule), and 24.3% and 53.7% received the BD plus at least two pentavalent vaccine doses within the recommended timeframes (three-dose schedule). In logistic regression models, home birth, dry season birth, and birth in 2016 were all associated with non-adherence to the recommended BD and three-dose schedules. Living over three kilometres from the nearest healthcare post, being the firstborn, and living in an agriculturally poorer household were only associated with non-adherence to the three-dose schedule. The substantial proportion of children not vaccinated according to recommended schedules highlights the importance of considering vaccination timeliness when evaluating vaccination programme effectiveness. Outreach vaccination activities and incentives to bring children born at home to healthcare facilities within 24 h of birth, must be strengthened to improve timely HBV vaccination. |
| first_indexed | 2024-03-10T11:22:59Z |
| format | Article |
| id | doaj.art-79c398c891b94d56abdf7362a0d7c186 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-10T11:22:59Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-79c398c891b94d56abdf7362a0d7c1862023-11-21T19:51:52ZengMDPI AGVaccines2076-393X2021-05-019551010.3390/vaccines9050510Hepatitis B Vaccination in Senegalese Children: Coverage, Timeliness, and Sociodemographic Determinants of Non-Adherence to Immunisation Schedules (ANRS 12356 AmBASS Survey)Lauren Périères0Fabienne Marcellin1Gora Lo2Camelia Protopopescu3El Hadji Ba4Marion Coste5Coumba Touré Kane6Gwenaëlle Maradan7Aldiouma Diallo8Cheikh Sokhna9Sylvie Boyer10on behalf of the ANRS 12356 AmBASS Survey Study GroupVITROME, Campus IRD-UCAD, CP 18524 Dakar, SenegalInserm, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l’Information Médicale, ISSPAM, Aix Marseille University, 13385 Marseille, FranceInstitut de Recherche en Santé de Surveillance Epidémiologique et de Formation, BP 7325 Diamniadio, SenegalInserm, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l’Information Médicale, ISSPAM, Aix Marseille University, 13385 Marseille, FranceVITROME, Campus IRD-UCAD, CP 18524 Dakar, SenegalInserm, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l’Information Médicale, ISSPAM, Aix Marseille University, 13385 Marseille, FranceInstitut de Recherche en Santé de Surveillance Epidémiologique et de Formation, BP 7325 Diamniadio, SenegalInserm, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l’Information Médicale, ISSPAM, Aix Marseille University, 13385 Marseille, FranceVITROME, Campus IRD-UCAD, CP 18524 Dakar, SenegalIRD, SSA, VITROME, Aix Marseille University, 13385 Marseille, FranceInserm, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l’Information Médicale, ISSPAM, Aix Marseille University, 13385 Marseille, FranceDetailed knowledge about hepatitis B virus (HBV) vaccination coverage and timeliness for sub-Saharan Africa is scarce. We used data from a community-based cross-sectional survey conducted in 2018–2019 in the area of Niakhar, Senegal, to estimate coverage, timeliness, and factors associated with non-adherence to the World Health Organisation-recommended vaccination schedules in children born in 2016 (year of the birth dose (BD) introduction in Senegal) and 2017–2018. Vaccination status was assessed from vaccination cards, surveillance data, and healthcare post vaccination records. Among 241 children with available data, for 2016 and 2017–2018, respectively, 31.0% and 66.8% received the BD within 24 h of birth (BD schedule), and 24.3% and 53.7% received the BD plus at least two pentavalent vaccine doses within the recommended timeframes (three-dose schedule). In logistic regression models, home birth, dry season birth, and birth in 2016 were all associated with non-adherence to the recommended BD and three-dose schedules. Living over three kilometres from the nearest healthcare post, being the firstborn, and living in an agriculturally poorer household were only associated with non-adherence to the three-dose schedule. The substantial proportion of children not vaccinated according to recommended schedules highlights the importance of considering vaccination timeliness when evaluating vaccination programme effectiveness. Outreach vaccination activities and incentives to bring children born at home to healthcare facilities within 24 h of birth, must be strengthened to improve timely HBV vaccination.https://www.mdpi.com/2076-393X/9/5/510birth dose vaccinationhepatitis B vaccinepentavalent vaccinationSenegalvaccination timelinessvaccination coverage |
| spellingShingle | Lauren Périères Fabienne Marcellin Gora Lo Camelia Protopopescu El Hadji Ba Marion Coste Coumba Touré Kane Gwenaëlle Maradan Aldiouma Diallo Cheikh Sokhna Sylvie Boyer on behalf of the ANRS 12356 AmBASS Survey Study Group Hepatitis B Vaccination in Senegalese Children: Coverage, Timeliness, and Sociodemographic Determinants of Non-Adherence to Immunisation Schedules (ANRS 12356 AmBASS Survey) Vaccines birth dose vaccination hepatitis B vaccine pentavalent vaccination Senegal vaccination timeliness vaccination coverage |
| title | Hepatitis B Vaccination in Senegalese Children: Coverage, Timeliness, and Sociodemographic Determinants of Non-Adherence to Immunisation Schedules (ANRS 12356 AmBASS Survey) |
| title_full | Hepatitis B Vaccination in Senegalese Children: Coverage, Timeliness, and Sociodemographic Determinants of Non-Adherence to Immunisation Schedules (ANRS 12356 AmBASS Survey) |
| title_fullStr | Hepatitis B Vaccination in Senegalese Children: Coverage, Timeliness, and Sociodemographic Determinants of Non-Adherence to Immunisation Schedules (ANRS 12356 AmBASS Survey) |
| title_full_unstemmed | Hepatitis B Vaccination in Senegalese Children: Coverage, Timeliness, and Sociodemographic Determinants of Non-Adherence to Immunisation Schedules (ANRS 12356 AmBASS Survey) |
| title_short | Hepatitis B Vaccination in Senegalese Children: Coverage, Timeliness, and Sociodemographic Determinants of Non-Adherence to Immunisation Schedules (ANRS 12356 AmBASS Survey) |
| title_sort | hepatitis b vaccination in senegalese children coverage timeliness and sociodemographic determinants of non adherence to immunisation schedules anrs 12356 ambass survey |
| topic | birth dose vaccination hepatitis B vaccine pentavalent vaccination Senegal vaccination timeliness vaccination coverage |
| url | https://www.mdpi.com/2076-393X/9/5/510 |
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