Evaluation of the Appropriate Use of Coronary Computed Tomography Angiography: A Retrospective, Single-Center Analysis

Purpose: We assessed the application of appropriate use criteria of coronary computed tomography angiography (CCTA) in comparison to invasive coronary angiography results and revascularization rates in patients with coronary artery disease (CAD). Methods: 1305 patients referred to invasive coronary...

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Main Authors: Katharina Birkl, Christoph Beyer, Fabian Plank, Gudrun Maria Feuchtner, Guy Friedrich
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/9/6/180
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author Katharina Birkl
Christoph Beyer
Fabian Plank
Gudrun Maria Feuchtner
Guy Friedrich
author_facet Katharina Birkl
Christoph Beyer
Fabian Plank
Gudrun Maria Feuchtner
Guy Friedrich
author_sort Katharina Birkl
collection DOAJ
description Purpose: We assessed the application of appropriate use criteria of coronary computed tomography angiography (CCTA) in comparison to invasive coronary angiography results and revascularization rates in patients with coronary artery disease (CAD). Methods: 1305 patients referred to invasive coronary angiography (ICA) after CCTA were evaluated retrospectively. The primary indication for CCTA was assessed according to the consensus for intermediate-risk (15–85% pre-test probability) into appropriate (A), inappropriate (I), and uncertain while referring to published guidelines. Patients’ risk factors, angina, and heart failure symptoms (Canadian Cardiovascular Society classification (CCSC), New York Heart Association (NYHA); clinical data; and ICA results were gathered. Results: Of 1305 patients referred to CCTA prior to ICA, 496 (38.0%) were appropriate, 766 (56.9%) inappropriate, and 43 (3.3%) uncertain. Of 766 patients with inappropriate CCTA referrals, 370 (48.3%) were classified as “inappropriately low” (<15% pre-test probability) and 396 (51.7%) as “inappropriately high” (>85%) in regard to the recommended CCTA utilization. Sub-analysis of the adherence to the appropriate use criteria did not differ between the source of the referring physicians (intramural tertiary, private practice primary care, or external secondary care hospitals). Obstructive CAD with subsequent revascularization rates (total of 39.2%) did not differ significantly between the appropriate (38.3%), inappropriate (41.0%), or uncertain (23.3%) groups (<i>p</i> = 0.068). Conclusion: The total coronary revascularization rate after CCTA was 39.2% and not different among low, intermediate, and pre-test probability groups. These findings support the role of CCTA as an excellent gatekeeper in patients with suspected obstructive CAD even beyond pre-test probability calculation models.
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spelling doaj.art-79c4ae42885a44a9a927d9e6ded655002023-11-23T17:12:33ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252022-06-019618010.3390/jcdd9060180Evaluation of the Appropriate Use of Coronary Computed Tomography Angiography: A Retrospective, Single-Center AnalysisKatharina Birkl0Christoph Beyer1Fabian Plank2Gudrun Maria Feuchtner3Guy Friedrich4Department of Radiology, Innsbruck Medical University, 6020 Innsbruck, AustriaDepartment of Radiology, Innsbruck Medical University, 6020 Innsbruck, AustriaDepartment of Internal Medicine III–Cardiology and Angiology, Innsbruck Medical University, 6020 Innsbruck, AustriaDepartment of Radiology, Innsbruck Medical University, 6020 Innsbruck, AustriaDepartment of Internal Medicine III–Cardiology and Angiology, Innsbruck Medical University, 6020 Innsbruck, AustriaPurpose: We assessed the application of appropriate use criteria of coronary computed tomography angiography (CCTA) in comparison to invasive coronary angiography results and revascularization rates in patients with coronary artery disease (CAD). Methods: 1305 patients referred to invasive coronary angiography (ICA) after CCTA were evaluated retrospectively. The primary indication for CCTA was assessed according to the consensus for intermediate-risk (15–85% pre-test probability) into appropriate (A), inappropriate (I), and uncertain while referring to published guidelines. Patients’ risk factors, angina, and heart failure symptoms (Canadian Cardiovascular Society classification (CCSC), New York Heart Association (NYHA); clinical data; and ICA results were gathered. Results: Of 1305 patients referred to CCTA prior to ICA, 496 (38.0%) were appropriate, 766 (56.9%) inappropriate, and 43 (3.3%) uncertain. Of 766 patients with inappropriate CCTA referrals, 370 (48.3%) were classified as “inappropriately low” (<15% pre-test probability) and 396 (51.7%) as “inappropriately high” (>85%) in regard to the recommended CCTA utilization. Sub-analysis of the adherence to the appropriate use criteria did not differ between the source of the referring physicians (intramural tertiary, private practice primary care, or external secondary care hospitals). Obstructive CAD with subsequent revascularization rates (total of 39.2%) did not differ significantly between the appropriate (38.3%), inappropriate (41.0%), or uncertain (23.3%) groups (<i>p</i> = 0.068). Conclusion: The total coronary revascularization rate after CCTA was 39.2% and not different among low, intermediate, and pre-test probability groups. These findings support the role of CCTA as an excellent gatekeeper in patients with suspected obstructive CAD even beyond pre-test probability calculation models.https://www.mdpi.com/2308-3425/9/6/180coronary computed tomography angiographyappropriate usecoronary artery diseaseinvasive coronary angiographypercutaneous coronary intervention
spellingShingle Katharina Birkl
Christoph Beyer
Fabian Plank
Gudrun Maria Feuchtner
Guy Friedrich
Evaluation of the Appropriate Use of Coronary Computed Tomography Angiography: A Retrospective, Single-Center Analysis
Journal of Cardiovascular Development and Disease
coronary computed tomography angiography
appropriate use
coronary artery disease
invasive coronary angiography
percutaneous coronary intervention
title Evaluation of the Appropriate Use of Coronary Computed Tomography Angiography: A Retrospective, Single-Center Analysis
title_full Evaluation of the Appropriate Use of Coronary Computed Tomography Angiography: A Retrospective, Single-Center Analysis
title_fullStr Evaluation of the Appropriate Use of Coronary Computed Tomography Angiography: A Retrospective, Single-Center Analysis
title_full_unstemmed Evaluation of the Appropriate Use of Coronary Computed Tomography Angiography: A Retrospective, Single-Center Analysis
title_short Evaluation of the Appropriate Use of Coronary Computed Tomography Angiography: A Retrospective, Single-Center Analysis
title_sort evaluation of the appropriate use of coronary computed tomography angiography a retrospective single center analysis
topic coronary computed tomography angiography
appropriate use
coronary artery disease
invasive coronary angiography
percutaneous coronary intervention
url https://www.mdpi.com/2308-3425/9/6/180
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AT fabianplank evaluationoftheappropriateuseofcoronarycomputedtomographyangiographyaretrospectivesinglecenteranalysis
AT gudrunmariafeuchtner evaluationoftheappropriateuseofcoronarycomputedtomographyangiographyaretrospectivesinglecenteranalysis
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