A Microbiota-Dependent Response to Anticancer Treatment in an In Vitro Human Microbiota Model: A Pilot Study With Hydroxycarbamide and Daunorubicin

A Microbiota-Dependent Response to Anticancer Treatment in an In Vitro Human Microbiota Model: A Pilot Study With Hydroxycarbamide and Daunorubicin

BackgroundAnticancer drug efficacy is linked to the gut microbiota’s composition, and there is a dire need to better understand these interactions for personalized medicine. In vitro microbiota models are promising tools for studies requiring controlled and repeatable conditions. We evaluated the im...

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Bibliographic Details
Main Authors: Claire Amaris Hobson, Lucile Vigué, Mélanie Magnan, Benoit Chassaing, Sabrine Naimi, Benoit Gachet, Pauline Claraz, Thomas Storme, Stephane Bonacorsi, Olivier Tenaillon, André Birgy
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
gut microbiota
in vitro microbiota model
MBRA
hydroxycarbamide
daunorubicin
anticancer treatment and bacteria
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.886447/full

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