Canal cristae growth and fiber extension to the outer hair cells of the mouse ear require Prox1 activity.
The homeobox gene Prox1 is required for lens, retina, pancreas, liver, and lymphatic vasculature development and is expressed in inner ear supporting cells and neurons.We have investigated the role of Prox1 in the developing mouse ear taking advantage of available standard and conditional Prox1 muta...
Main Authors: | Bernd Fritzsch, Miriam Dillard, Alfonso Lavado, Natasha L Harvey, Israt Jahan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-02-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2826422?pdf=render |
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