Phytochemistry and Pharmacology of Sesquiterpenoids from <i>Atractylodes</i> DC. Genus Rhizomes

The rhizomes of the genus <i>Atractylodes</i> DC. consist of various bioactive components, including sesquiterpenes, which have attracted a great deal of research interest in recent years. In the present study, we reviewed the previously published literatures prior to November 2023 on th...

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Main Authors: Zhengyi Qu, Hongqun Liu, Zhenghai Zhang, Peihe Zheng, Shuting Zhao, Wei Hou
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/6/1379
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author Zhengyi Qu
Hongqun Liu
Zhenghai Zhang
Peihe Zheng
Shuting Zhao
Wei Hou
author_facet Zhengyi Qu
Hongqun Liu
Zhenghai Zhang
Peihe Zheng
Shuting Zhao
Wei Hou
author_sort Zhengyi Qu
collection DOAJ
description The rhizomes of the genus <i>Atractylodes</i> DC. consist of various bioactive components, including sesquiterpenes, which have attracted a great deal of research interest in recent years. In the present study, we reviewed the previously published literatures prior to November 2023 on the chemical structures, biosynthetic pathways, and pharmacological activities of the sesquiterpenoids from this genus via online databases such as Web of Science, Google Scholar, and ScienceDirect. Phytochemical studies have led to the identification of more than 160 sesquiterpenes, notably eudesmane-type sesquiterpenes. Many pharmacological activities have been demonstrated, particularly anticancer, anti-inflammatory, and antibacterial and antiviral activities. This review presents updated, comprehensive and categorized information on the phytochemistry and pharmacology of sesquiterpenes in <i>Atractylodes</i> DC., with the aim of offering guidance for the future exploitation and utilization of active ingredients in this genus.
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spelling doaj.art-79cb502806a44e3ab26eea20bea2255e2024-03-27T13:57:13ZengMDPI AGMolecules1420-30492024-03-01296137910.3390/molecules29061379Phytochemistry and Pharmacology of Sesquiterpenoids from <i>Atractylodes</i> DC. Genus RhizomesZhengyi Qu0Hongqun Liu1Zhenghai Zhang2Peihe Zheng3Shuting Zhao4Wei Hou5Institute of Special Wild Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun 130112, ChinaMedical School, Changchun Sci-Tech University, Changchun 130600, ChinaTraditional Chinese Medicine School, Jilin Agricultural Science and Technology University, Jilin 132109, ChinaTraditional Chinese Medicine School, Jilin Agricultural Science and Technology University, Jilin 132109, ChinaInstitute of Special Wild Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun 130112, ChinaInstitute of Special Wild Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun 130112, ChinaThe rhizomes of the genus <i>Atractylodes</i> DC. consist of various bioactive components, including sesquiterpenes, which have attracted a great deal of research interest in recent years. In the present study, we reviewed the previously published literatures prior to November 2023 on the chemical structures, biosynthetic pathways, and pharmacological activities of the sesquiterpenoids from this genus via online databases such as Web of Science, Google Scholar, and ScienceDirect. Phytochemical studies have led to the identification of more than 160 sesquiterpenes, notably eudesmane-type sesquiterpenes. Many pharmacological activities have been demonstrated, particularly anticancer, anti-inflammatory, and antibacterial and antiviral activities. This review presents updated, comprehensive and categorized information on the phytochemistry and pharmacology of sesquiterpenes in <i>Atractylodes</i> DC., with the aim of offering guidance for the future exploitation and utilization of active ingredients in this genus.https://www.mdpi.com/1420-3049/29/6/1379<i>Atractylodes</i> DC. rhizomessesquiterpeneseudesmane-typephytochemistrybiosynthetic pathwayspharmacology
spellingShingle Zhengyi Qu
Hongqun Liu
Zhenghai Zhang
Peihe Zheng
Shuting Zhao
Wei Hou
Phytochemistry and Pharmacology of Sesquiterpenoids from <i>Atractylodes</i> DC. Genus Rhizomes
Molecules
<i>Atractylodes</i> DC. rhizomes
sesquiterpenes
eudesmane-type
phytochemistry
biosynthetic pathways
pharmacology
title Phytochemistry and Pharmacology of Sesquiterpenoids from <i>Atractylodes</i> DC. Genus Rhizomes
title_full Phytochemistry and Pharmacology of Sesquiterpenoids from <i>Atractylodes</i> DC. Genus Rhizomes
title_fullStr Phytochemistry and Pharmacology of Sesquiterpenoids from <i>Atractylodes</i> DC. Genus Rhizomes
title_full_unstemmed Phytochemistry and Pharmacology of Sesquiterpenoids from <i>Atractylodes</i> DC. Genus Rhizomes
title_short Phytochemistry and Pharmacology of Sesquiterpenoids from <i>Atractylodes</i> DC. Genus Rhizomes
title_sort phytochemistry and pharmacology of sesquiterpenoids from i atractylodes i dc genus rhizomes
topic <i>Atractylodes</i> DC. rhizomes
sesquiterpenes
eudesmane-type
phytochemistry
biosynthetic pathways
pharmacology
url https://www.mdpi.com/1420-3049/29/6/1379
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