Discovery of a novel hybrid coumarin-hydroxamate conjugate targeting the HDAC1-Sp1-FOSL2 signaling axis for breast cancer therapy
Abstract Background Breast cancer is one of the most lethal cancers in women. Despite significant advances in the diagnosis and treatment of breast cancer, many patients still succumb to this disease, and thus, novel effective treatments are urgently needed. Natural product coumarin has been broadly...
Principais autores: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
BMC
2024-07-01
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coleção: | Cell Communication and Signaling |
Assuntos: | |
Acesso em linha: | https://doi.org/10.1186/s12964-024-01733-4 |