Effects of knots on protein folding properties.
This work explores the impact of knots, knot depth and motif of the threading terminus in protein folding properties (kinetics, thermodynamics and mechanism) via extensive Monte Carlo simulations of lattice models. A knotted backbone has no effect on protein thermodynamic stability but it may affect...
Main Authors: | Miguel A Soler, Patrícia F N Faísca |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3762781?pdf=render |
Similar Items
-
How difficult is it to fold a knotted protein? In silico insights from surface-tethered folding experiments.
by: Miguel A Soler, et al.
Published: (2012-01-01) -
Knotted proteins: A tangled tale of Structural Biology
by: Patrícia F.N. Faísca
Published: (2015-01-01) -
Polymer uncrossing and knotting in protein folding, and their role in minimal folding pathways.
by: Ali R Mohazab, et al.
Published: (2013-01-01) -
CURRENT APPROACHES TO DISENTANGLE THE MYSTERY OF KNOTTED PROTEIN FOLDING
by: PAWEL DABROWSKI-TUMANSKI, et al.
Published: (2016-10-01) -
The role of non-native interactions in the folding of knotted proteins.
by: Tatjana Skrbić, et al.
Published: (2012-01-01)