Early menarche and its consequence in Korean female: reducing fructose intake could be one solution
The mean age at menarche (AAM) of Korean females has been rapidly decreasing over the last 50 years; currently, the prevalence of early menarche (<12 years) is 22.3%. Female adolescents who experience early menarche are known to be at greater risk of psychosocial and behavioral problems along wit...
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Format: | Article |
Language: | English |
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The Korean Pediatric Society
2021-01-01
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Series: | Clinical and Experimental Pediatrics |
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Online Access: | http://www.e-cep.org/upload/pdf/cep-2019-00353.pdf |
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author | Ji Hyun Kim Jung Sub Lim |
author_facet | Ji Hyun Kim Jung Sub Lim |
author_sort | Ji Hyun Kim |
collection | DOAJ |
description | The mean age at menarche (AAM) of Korean females has been rapidly decreasing over the last 50 years; currently, the prevalence of early menarche (<12 years) is 22.3%. Female adolescents who experience early menarche are known to be at greater risk of psychosocial and behavioral problems along with several physical health problems such as menstrual problems. They also tend to achieve a shorter final height and develop obesity. Population-based Korean studies have shown a strong association between early menarche and the risk of obesity, insulin resistance, metabolic syndrome, nonalcoholic fatty liver disease, diabetes, breast cancer, and cardiovascular disease in adulthood. Although the exact mechanism of how early menarche causes cardiometabolic derangement in later adulthood is unknown, childhood obesity and insulin resistance might be major contributors. Recent studies demonstrated that an excessive consumption of fructose might underlie the development of obesity and insulin resistance along with an earlier AAM. A positive association was observed between sugar-sweetened beverages (a major source of fructose) intake and obesity, metabolic syndrome, insulin resistance, and cardiometabolic risk in Korean females. In pediatrics, establishing risk factors is important in preventing disease in later life. In this regard, early menarche is a simple and good marker for the management of cardiometabolic diseases in adulthood. Decreasing one’s fructose intake might prevent early menarche as well as the development of obesity, insulin resistance, and cardiometabolic diseases. |
first_indexed | 2024-12-17T04:52:02Z |
format | Article |
id | doaj.art-79ce47160b514d02a5ff99e08609cdec |
institution | Directory Open Access Journal |
issn | 2713-4148 |
language | English |
last_indexed | 2024-12-17T04:52:02Z |
publishDate | 2021-01-01 |
publisher | The Korean Pediatric Society |
record_format | Article |
series | Clinical and Experimental Pediatrics |
spelling | doaj.art-79ce47160b514d02a5ff99e08609cdec2022-12-21T22:02:52ZengThe Korean Pediatric SocietyClinical and Experimental Pediatrics2713-41482021-01-01641122010.3345/cep.2019.0035320125553646Early menarche and its consequence in Korean female: reducing fructose intake could be one solutionJi Hyun Kim0Jung Sub Lim1 Department of Pediatrics, Dongguk University Ilsan Hospital, Goyang, Korea Department of Pediatrics, Korea Cancer Center Hospital, Seoul, KoreaThe mean age at menarche (AAM) of Korean females has been rapidly decreasing over the last 50 years; currently, the prevalence of early menarche (<12 years) is 22.3%. Female adolescents who experience early menarche are known to be at greater risk of psychosocial and behavioral problems along with several physical health problems such as menstrual problems. They also tend to achieve a shorter final height and develop obesity. Population-based Korean studies have shown a strong association between early menarche and the risk of obesity, insulin resistance, metabolic syndrome, nonalcoholic fatty liver disease, diabetes, breast cancer, and cardiovascular disease in adulthood. Although the exact mechanism of how early menarche causes cardiometabolic derangement in later adulthood is unknown, childhood obesity and insulin resistance might be major contributors. Recent studies demonstrated that an excessive consumption of fructose might underlie the development of obesity and insulin resistance along with an earlier AAM. A positive association was observed between sugar-sweetened beverages (a major source of fructose) intake and obesity, metabolic syndrome, insulin resistance, and cardiometabolic risk in Korean females. In pediatrics, establishing risk factors is important in preventing disease in later life. In this regard, early menarche is a simple and good marker for the management of cardiometabolic diseases in adulthood. Decreasing one’s fructose intake might prevent early menarche as well as the development of obesity, insulin resistance, and cardiometabolic diseases.http://www.e-cep.org/upload/pdf/cep-2019-00353.pdfmenarchemetabolic diseasefructoseinsulin resistanceobesitypathophysiology |
spellingShingle | Ji Hyun Kim Jung Sub Lim Early menarche and its consequence in Korean female: reducing fructose intake could be one solution Clinical and Experimental Pediatrics menarche metabolic disease fructose insulin resistance obesity pathophysiology |
title | Early menarche and its consequence in Korean female: reducing fructose intake could be one solution |
title_full | Early menarche and its consequence in Korean female: reducing fructose intake could be one solution |
title_fullStr | Early menarche and its consequence in Korean female: reducing fructose intake could be one solution |
title_full_unstemmed | Early menarche and its consequence in Korean female: reducing fructose intake could be one solution |
title_short | Early menarche and its consequence in Korean female: reducing fructose intake could be one solution |
title_sort | early menarche and its consequence in korean female reducing fructose intake could be one solution |
topic | menarche metabolic disease fructose insulin resistance obesity pathophysiology |
url | http://www.e-cep.org/upload/pdf/cep-2019-00353.pdf |
work_keys_str_mv | AT jihyunkim earlymenarcheanditsconsequenceinkoreanfemalereducingfructoseintakecouldbeonesolution AT jungsublim earlymenarcheanditsconsequenceinkoreanfemalereducingfructoseintakecouldbeonesolution |