EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT)
<em>The case of early onset and severe course of systemic juvenile rheumatoid arthritis refractory to classic immunosuppressive agents and blockers of tumor necrosis factor (TNF) is presented in this article. Successful clinical use of biological agent rituximab was described. extraarticular s...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2008-01-01
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| Series: | Вопросы современной педиатрии |
| Online Access: | http://vsp.spr-journal.ru:80/jour/article/view/1402 |
| _version_ | 1827848244524220416 |
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| author | E.I. Alexeeva E.L. Semikina T.M. Bzarova S.I. Valieva R.V. Denisova A.O. Lisitsin E.Yu. Gudkova S.S. Akulova E.A. Kopyl'tsova |
| author_facet | E.I. Alexeeva E.L. Semikina T.M. Bzarova S.I. Valieva R.V. Denisova A.O. Lisitsin E.Yu. Gudkova S.S. Akulova E.A. Kopyl'tsova |
| author_sort | E.I. Alexeeva |
| collection | DOAJ |
| description | <em>The case of early onset and severe course of systemic juvenile rheumatoid arthritis refractory to classic immunosuppressive agents and blockers of tumor necrosis factor (TNF) is presented in this article. Successful clinical use of biological agent rituximab was described. extraarticular symptoms of disease were stopped by 6 week of treatment, and acute inflammatory alteration of articulations was reduced by 16 week, the range of motions was completely restored. This case report demonstrates high activity of rituximab. A clinical and laboratory remission of disease in patient with severe course of systemic juvenile rheumatoid arthritis continues for a 32 weeks.</em><br /><strong><em>Key words: children, juvenile rheumatoid arthritis, rituximab.</em></strong> |
| first_indexed | 2024-03-12T09:44:10Z |
| format | Article |
| id | doaj.art-79d2b84f9d024ad49e00374e54896067 |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2024-03-12T09:44:10Z |
| publishDate | 2008-01-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-79d2b84f9d024ad49e00374e548960672023-09-02T13:00:52Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352008-01-017379851402EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT)E.I. Alexeeva0E.L. Semikina1T.M. Bzarova2S.I. Valieva3R.V. Denisova4A.O. Lisitsin5E.Yu. Gudkova6S.S. Akulova7E.A. Kopyl'tsova8Scientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow<em>The case of early onset and severe course of systemic juvenile rheumatoid arthritis refractory to classic immunosuppressive agents and blockers of tumor necrosis factor (TNF) is presented in this article. Successful clinical use of biological agent rituximab was described. extraarticular symptoms of disease were stopped by 6 week of treatment, and acute inflammatory alteration of articulations was reduced by 16 week, the range of motions was completely restored. This case report demonstrates high activity of rituximab. A clinical and laboratory remission of disease in patient with severe course of systemic juvenile rheumatoid arthritis continues for a 32 weeks.</em><br /><strong><em>Key words: children, juvenile rheumatoid arthritis, rituximab.</em></strong>http://vsp.spr-journal.ru:80/jour/article/view/1402 |
| spellingShingle | E.I. Alexeeva E.L. Semikina T.M. Bzarova S.I. Valieva R.V. Denisova A.O. Lisitsin E.Yu. Gudkova S.S. Akulova E.A. Kopyl'tsova EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT) Вопросы современной педиатрии |
| title | EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT) |
| title_full | EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT) |
| title_fullStr | EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT) |
| title_full_unstemmed | EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT) |
| title_short | EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT) |
| title_sort | experience of clinical use of rituximab in patient with systemic juvenile arthritis a case report |
| url | http://vsp.spr-journal.ru:80/jour/article/view/1402 |
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