Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acids
Palladium catalysed C-H functionalization ofsp3carbons typically requires the installation and subsequent removal of a temporary directing group. Here the authors report a method allowing C-H functionalization in carboxylic acids in which the carboxylate acts as a directing group.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2017-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms14904 |
| _version_ | 1819129209753174016 |
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| author | Yan Zhu Xiaolan Chen Chunchen Yuan Guobao Li Jingyu Zhang Yingsheng Zhao |
| author_facet | Yan Zhu Xiaolan Chen Chunchen Yuan Guobao Li Jingyu Zhang Yingsheng Zhao |
| author_sort | Yan Zhu |
| collection | DOAJ |
| description | Palladium catalysed C-H functionalization ofsp3carbons typically requires the installation and subsequent removal of a temporary directing group. Here the authors report a method allowing C-H functionalization in carboxylic acids in which the carboxylate acts as a directing group. |
| first_indexed | 2024-12-22T08:40:05Z |
| format | Article |
| id | doaj.art-79d36e5bbcad49988d35ee9fadc52393 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-22T08:40:05Z |
| publishDate | 2017-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-79d36e5bbcad49988d35ee9fadc523932022-12-21T18:32:15ZengNature PortfolioNature Communications2041-17232017-04-01811810.1038/ncomms14904Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acidsYan Zhu0Xiaolan Chen1Chunchen Yuan2Guobao Li3Jingyu Zhang4Yingsheng Zhao5Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow UniversityKey Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow UniversityKey Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow UniversityKey Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow UniversityKey Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow UniversityKey Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow UniversityPalladium catalysed C-H functionalization ofsp3carbons typically requires the installation and subsequent removal of a temporary directing group. Here the authors report a method allowing C-H functionalization in carboxylic acids in which the carboxylate acts as a directing group.https://doi.org/10.1038/ncomms14904 |
| spellingShingle | Yan Zhu Xiaolan Chen Chunchen Yuan Guobao Li Jingyu Zhang Yingsheng Zhao Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acids Nature Communications |
| title | Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acids |
| title_full | Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acids |
| title_fullStr | Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acids |
| title_full_unstemmed | Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acids |
| title_short | Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acids |
| title_sort | pd catalysed ligand enabled carboxylate directed highly regioselective arylation of aliphatic acids |
| url | https://doi.org/10.1038/ncomms14904 |
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