The Impact of Orthodontic Treatment on Teeth Previously Treated with Regenerative Endodontics: A Systematic Review

Objective: To assess the tooth survival rates, adverse events, and need for further treatment of teeth previously treated with regenerative endodontics undergoing orthodontic treatment. Material and Methods: A literature search was performed using MEDLINE, EMBASE, Cochrane, Scopus, and Lilacs databa...

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Main Authors: Cristina Bucchi, Alain Arias-Betancur, Nicolás Badilla-Wenzel, Carlos Zaror
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/14/1/210
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author Cristina Bucchi
Alain Arias-Betancur
Nicolás Badilla-Wenzel
Carlos Zaror
author_facet Cristina Bucchi
Alain Arias-Betancur
Nicolás Badilla-Wenzel
Carlos Zaror
author_sort Cristina Bucchi
collection DOAJ
description Objective: To assess the tooth survival rates, adverse events, and need for further treatment of teeth previously treated with regenerative endodontics undergoing orthodontic treatment. Material and Methods: A literature search was performed using MEDLINE, EMBASE, Cochrane, Scopus, and Lilacs databases, grey literature, and endodontic journals, and the date of the last search was 20 April 2022. The included studies involved patients undergoing orthodontic treatment and at least one tooth that was previously treated with regenerative endodontics. A narrative synthesis of the findings was made. The risk of bias and evidence quality were assessed using the Effective Public Health Practice Project tool and the GRADE approach. Results: Five case reports included seven patients and eight teeth with a follow-up of 4 to 11 years. The overall risk of bias was high, and the certainty of evidence was very low. The survival rate was 87.5%. Adverse effects included sinus tracts, root resorption, symptomatology, apical periodontitis, and intracanal tissue necrosis. Five out of eight teeth required further intervention after orthodontics. Conclusions: A high prevalence of adverse effects and further intervention is observed in teeth treated with regenerative endodontics undergoing orthodontic treatment. The low quality of evidence highlights the need for comparative studies and evidence-based guidelines for managing these teeth during orthodontic treatment.
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spelling doaj.art-79d584399c6c42b18d932dadc724755a2024-01-10T14:51:21ZengMDPI AGApplied Sciences2076-34172023-12-0114121010.3390/app14010210The Impact of Orthodontic Treatment on Teeth Previously Treated with Regenerative Endodontics: A Systematic ReviewCristina Bucchi0Alain Arias-Betancur1Nicolás Badilla-Wenzel2Carlos Zaror3Departament of Integral Adult Dentistry, Faculty of Dentistry, Universidad de La Frontera, Temuco 4811230, ChileDepartament of Integral Adult Dentistry, Faculty of Dentistry, Universidad de La Frontera, Temuco 4811230, ChileDepartament of Integral Adult Dentistry, Faculty of Dentistry, Universidad de La Frontera, Temuco 4811230, ChileCenter for Research in Epidemiology, Economics and Oral Public Health (CIEESPO), Universidad de La Frontera, Temuco 4811230, ChileObjective: To assess the tooth survival rates, adverse events, and need for further treatment of teeth previously treated with regenerative endodontics undergoing orthodontic treatment. Material and Methods: A literature search was performed using MEDLINE, EMBASE, Cochrane, Scopus, and Lilacs databases, grey literature, and endodontic journals, and the date of the last search was 20 April 2022. The included studies involved patients undergoing orthodontic treatment and at least one tooth that was previously treated with regenerative endodontics. A narrative synthesis of the findings was made. The risk of bias and evidence quality were assessed using the Effective Public Health Practice Project tool and the GRADE approach. Results: Five case reports included seven patients and eight teeth with a follow-up of 4 to 11 years. The overall risk of bias was high, and the certainty of evidence was very low. The survival rate was 87.5%. Adverse effects included sinus tracts, root resorption, symptomatology, apical periodontitis, and intracanal tissue necrosis. Five out of eight teeth required further intervention after orthodontics. Conclusions: A high prevalence of adverse effects and further intervention is observed in teeth treated with regenerative endodontics undergoing orthodontic treatment. The low quality of evidence highlights the need for comparative studies and evidence-based guidelines for managing these teeth during orthodontic treatment.https://www.mdpi.com/2076-3417/14/1/210adverse effectsorthodontic treatmentregenerative endodonticsrevitalizationtooth movement techniques
spellingShingle Cristina Bucchi
Alain Arias-Betancur
Nicolás Badilla-Wenzel
Carlos Zaror
The Impact of Orthodontic Treatment on Teeth Previously Treated with Regenerative Endodontics: A Systematic Review
Applied Sciences
adverse effects
orthodontic treatment
regenerative endodontics
revitalization
tooth movement techniques
title The Impact of Orthodontic Treatment on Teeth Previously Treated with Regenerative Endodontics: A Systematic Review
title_full The Impact of Orthodontic Treatment on Teeth Previously Treated with Regenerative Endodontics: A Systematic Review
title_fullStr The Impact of Orthodontic Treatment on Teeth Previously Treated with Regenerative Endodontics: A Systematic Review
title_full_unstemmed The Impact of Orthodontic Treatment on Teeth Previously Treated with Regenerative Endodontics: A Systematic Review
title_short The Impact of Orthodontic Treatment on Teeth Previously Treated with Regenerative Endodontics: A Systematic Review
title_sort impact of orthodontic treatment on teeth previously treated with regenerative endodontics a systematic review
topic adverse effects
orthodontic treatment
regenerative endodontics
revitalization
tooth movement techniques
url https://www.mdpi.com/2076-3417/14/1/210
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