Maternal androgen excess significantly impairs sexual behavior in male and female mouse offspring: Perspective for a biological origin of sexual dysfunction in PCOS

Maternal androgen excess significantly impairs sexual behavior in male and female mouse offspring: Perspective for a biological origin of sexual dysfunction in PCOS

IntroductionPolycystic ovary syndrome (PCOS) is the most common infertility disorder worldwide, typically characterised by high circulating androgen levels, oligo- or anovulation, and polycystic ovarian morphology. Sexual dysfunction, including decreased sexual desire and increased sexual dissatisfa...

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Bibliographic Details
Main Authors: Nina M. Donaldson, Melanie Prescott, Amy Ruddenklau, Rebecca E. Campbell, Elodie Desroziers
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Endocrinology
Subjects:
androgen
PCOS (polycystic ovary syndrome)
sexual behavior
DHT (5α-dihydrotestosterone)
sexual dysfunction (biological)
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1116482/full

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