Changes in the Incidence of Bronchopulmonary Dysplasia among Preterm Infants in a Single Center over 10 Years
Purpose Bronchopulmonary dysplasia (BPD) is one of the most fatal respiratory morbidities in preterm infants, causing adverse respiratory and neurodevelopmental outcomes. Despite advances in neonatal ventilator care, the incidence of BPD has been static or even increased. The purpose of this study w...
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| Format: | Article |
| Language: | English |
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Korean Society of Neonatology
2020-02-01
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| Series: | Neonatal Medicine |
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| Online Access: | http://www.neo-med.org/upload/pdf/nm-2020-27-1-1.pdf |
| _version_ | 1819320052727414784 |
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| author | Ga Won Jeon |
| author_facet | Ga Won Jeon |
| author_sort | Ga Won Jeon |
| collection | DOAJ |
| description | Purpose Bronchopulmonary dysplasia (BPD) is one of the most fatal respiratory morbidities in preterm infants, causing adverse respiratory and neurodevelopmental outcomes. Despite advances in neonatal ventilator care, the incidence of BPD has been static or even increased. The purpose of this study was to evaluate the incidence of BPD in a single center over 10 years. Methods Preterm infants with gestational age (GA) <30 weeks who were admitted to Inje University Busan Paik Hospital from January 2009 to December 2018 and sur vived 28 days or more were enrolled. The incidence of BPD according to year and GA and the risk factors of BPD were evaluated. Results Among 629 infants, 521 infants who survived 28 days or more were enrolled (BPD group, n=252; non-BPD group, n=269). The incidence of BPD was 48.4%, with moderate to severe BPD accounting for 13.9%. In preterm infants with GA ≤25, 26 to 27, and 28 to 29 weeks, the incidences of BPD were 57.5%, 51.5%, and 14.6%, respectively, with moderate to severe BPD accounting for 23.8%, 10.5%, and 3.7%, respectively. The incidence of BPD decreased from 68% in 2009 to 34.3% in 2014. Subsequently, it increased. Surfactant re-dosing and patent ductus arteriosus were more frequent in the BPD group than in the non-BPD group. Conclusion BPD did not decrease over the previous 10 years despite advances in neonatal care. |
| first_indexed | 2024-12-24T11:13:27Z |
| format | Article |
| id | doaj.art-79dbf0aa06a54425913c6509fe5a9995 |
| institution | Directory Open Access Journal |
| issn | 2287-9412 2287-9803 |
| language | English |
| last_indexed | 2024-12-24T11:13:27Z |
| publishDate | 2020-02-01 |
| publisher | Korean Society of Neonatology |
| record_format | Article |
| series | Neonatal Medicine |
| spelling | doaj.art-79dbf0aa06a54425913c6509fe5a99952022-12-21T16:58:27ZengKorean Society of NeonatologyNeonatal Medicine2287-94122287-98032020-02-012711710.5385/nm.2020.27.1.1990Changes in the Incidence of Bronchopulmonary Dysplasia among Preterm Infants in a Single Center over 10 YearsGa Won Jeon0 Department of Pediatrics, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan, KoreaPurpose Bronchopulmonary dysplasia (BPD) is one of the most fatal respiratory morbidities in preterm infants, causing adverse respiratory and neurodevelopmental outcomes. Despite advances in neonatal ventilator care, the incidence of BPD has been static or even increased. The purpose of this study was to evaluate the incidence of BPD in a single center over 10 years. Methods Preterm infants with gestational age (GA) <30 weeks who were admitted to Inje University Busan Paik Hospital from January 2009 to December 2018 and sur vived 28 days or more were enrolled. The incidence of BPD according to year and GA and the risk factors of BPD were evaluated. Results Among 629 infants, 521 infants who survived 28 days or more were enrolled (BPD group, n=252; non-BPD group, n=269). The incidence of BPD was 48.4%, with moderate to severe BPD accounting for 13.9%. In preterm infants with GA ≤25, 26 to 27, and 28 to 29 weeks, the incidences of BPD were 57.5%, 51.5%, and 14.6%, respectively, with moderate to severe BPD accounting for 23.8%, 10.5%, and 3.7%, respectively. The incidence of BPD decreased from 68% in 2009 to 34.3% in 2014. Subsequently, it increased. Surfactant re-dosing and patent ductus arteriosus were more frequent in the BPD group than in the non-BPD group. Conclusion BPD did not decrease over the previous 10 years despite advances in neonatal care.http://www.neo-med.org/upload/pdf/nm-2020-27-1-1.pdfbronchopulmonary dysplasiainfant, prematureinfant, very low birth weightinfant, extremely low birth weightinfant, extremely premature |
| spellingShingle | Ga Won Jeon Changes in the Incidence of Bronchopulmonary Dysplasia among Preterm Infants in a Single Center over 10 Years Neonatal Medicine bronchopulmonary dysplasia infant, premature infant, very low birth weight infant, extremely low birth weight infant, extremely premature |
| title | Changes in the Incidence of Bronchopulmonary Dysplasia among Preterm Infants in a Single Center over 10 Years |
| title_full | Changes in the Incidence of Bronchopulmonary Dysplasia among Preterm Infants in a Single Center over 10 Years |
| title_fullStr | Changes in the Incidence of Bronchopulmonary Dysplasia among Preterm Infants in a Single Center over 10 Years |
| title_full_unstemmed | Changes in the Incidence of Bronchopulmonary Dysplasia among Preterm Infants in a Single Center over 10 Years |
| title_short | Changes in the Incidence of Bronchopulmonary Dysplasia among Preterm Infants in a Single Center over 10 Years |
| title_sort | changes in the incidence of bronchopulmonary dysplasia among preterm infants in a single center over 10 years |
| topic | bronchopulmonary dysplasia infant, premature infant, very low birth weight infant, extremely low birth weight infant, extremely premature |
| url | http://www.neo-med.org/upload/pdf/nm-2020-27-1-1.pdf |
| work_keys_str_mv | AT gawonjeon changesintheincidenceofbronchopulmonarydysplasiaamongpreterminfantsinasinglecenterover10years |