Solar radiation-assisted one-pot synthesis of 3-alkylated indoles under catalyst-free conditions
Solar radiation-assisted green approach was developed for the chemoselective synthesis of 3-alkylated indoles via Yonemitsu-type condensation under catalyst-free conditions. The desired products were formed by one-pot three-component reaction of indole, aromatic aldehydes, and β-dicarbonyl compounds...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-04-01
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| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535223000709 |
| _version_ | 1827998824171307008 |
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| author | Mohammad Pirbaba Rezvan Kardooni Ali Reza Kiasat Mohammad Sabaeian |
| author_facet | Mohammad Pirbaba Rezvan Kardooni Ali Reza Kiasat Mohammad Sabaeian |
| author_sort | Mohammad Pirbaba |
| collection | DOAJ |
| description | Solar radiation-assisted green approach was developed for the chemoselective synthesis of 3-alkylated indoles via Yonemitsu-type condensation under catalyst-free conditions. The desired products were formed by one-pot three-component reaction of indole, aromatic aldehydes, and β-dicarbonyl compounds in polyethylene glycol-400 (PEG-400). The scope and generality of the presented approach were extended by various aromatic aldehydes and CH activated compounds. Using non-volatile solvent and renewable energy resources, absence of any catalyst, energy conservation, and the selective production of heterodimer product instead of homodimer adducts such as bisindole or xanthine, increase the economic and environmental effectiveness of the present protocol. |
| first_indexed | 2024-04-10T05:49:48Z |
| format | Article |
| id | doaj.art-79df903d6f0045d78b91127a1d7cec40 |
| institution | Directory Open Access Journal |
| issn | 1878-5352 |
| language | English |
| last_indexed | 2024-04-10T05:49:48Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Arabian Journal of Chemistry |
| spelling | doaj.art-79df903d6f0045d78b91127a1d7cec402023-03-05T04:24:01ZengElsevierArabian Journal of Chemistry1878-53522023-04-01164104609Solar radiation-assisted one-pot synthesis of 3-alkylated indoles under catalyst-free conditionsMohammad Pirbaba0Rezvan Kardooni1Ali Reza Kiasat2Mohammad Sabaeian3Chemistry Department, College of Science, Shahid Chamran University of Ahvaz, Ahvaz, IranChemistry Department, College of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran; Corresponding author at: Chemistry Department, College of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran.Chemistry Department, College of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran; Geology and Geochemistry Research Centre (PGGRC), Shahid Chamran University of Ahvaz, Ahvaz, IranDepartment of Physics, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran; Centre for Research on Laser and Plasma, Shahid Chamran University of Ahvaz, Ahvaz, IranSolar radiation-assisted green approach was developed for the chemoselective synthesis of 3-alkylated indoles via Yonemitsu-type condensation under catalyst-free conditions. The desired products were formed by one-pot three-component reaction of indole, aromatic aldehydes, and β-dicarbonyl compounds in polyethylene glycol-400 (PEG-400). The scope and generality of the presented approach were extended by various aromatic aldehydes and CH activated compounds. Using non-volatile solvent and renewable energy resources, absence of any catalyst, energy conservation, and the selective production of heterodimer product instead of homodimer adducts such as bisindole or xanthine, increase the economic and environmental effectiveness of the present protocol.http://www.sciencedirect.com/science/article/pii/S18785352230007093-Alkylated IndolesSolar RadiationCatalyst-Free SynthesisGreen SynthesisOne- Pot Synthesis |
| spellingShingle | Mohammad Pirbaba Rezvan Kardooni Ali Reza Kiasat Mohammad Sabaeian Solar radiation-assisted one-pot synthesis of 3-alkylated indoles under catalyst-free conditions Arabian Journal of Chemistry 3-Alkylated Indoles Solar Radiation Catalyst-Free Synthesis Green Synthesis One- Pot Synthesis |
| title | Solar radiation-assisted one-pot synthesis of 3-alkylated indoles under catalyst-free conditions |
| title_full | Solar radiation-assisted one-pot synthesis of 3-alkylated indoles under catalyst-free conditions |
| title_fullStr | Solar radiation-assisted one-pot synthesis of 3-alkylated indoles under catalyst-free conditions |
| title_full_unstemmed | Solar radiation-assisted one-pot synthesis of 3-alkylated indoles under catalyst-free conditions |
| title_short | Solar radiation-assisted one-pot synthesis of 3-alkylated indoles under catalyst-free conditions |
| title_sort | solar radiation assisted one pot synthesis of 3 alkylated indoles under catalyst free conditions |
| topic | 3-Alkylated Indoles Solar Radiation Catalyst-Free Synthesis Green Synthesis One- Pot Synthesis |
| url | http://www.sciencedirect.com/science/article/pii/S1878535223000709 |
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