Experimental Studies and Modeling of the Degradation Process of Poly(Lactic-<i>co</i>-Glycolic Acid) Microspheres for Sustained Protein Release

Experimental Studies and Modeling of the Degradation Process of Poly(Lactic-<i>co</i>-Glycolic Acid) Microspheres for Sustained Protein Release

In this study, poly(lactic-<i>co</i>-glycolic acid) microspheres (PLGA MS)for controlled protein release by double emulsion-solvent evaporation were produced and characterized for their morphological and technological features. MS autocatalytic degradation was described by a mathematical...

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Bibliographic Details
Main Authors: Paolo Antonio Netti, Marco Biondi, Mariaenrica Frigione
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Polymers
Subjects:
degradation of PLGA
kinetics of degradation
PLGA microspheres
drug delivery
mathematical modeling
Online Access:https://www.mdpi.com/2073-4360/12/9/2042

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