The Relationship Between Diabetic Peripheral Neuropathy and (MPV) Mean Platelet Volume Values in Patients With Type 2 Diabetes Mellitus
Aim:We aimed to evaluate the relationship between diabetic peripheral neuropathy and MPV values in type 2 diabetes mellitus patients.Materials and Methods:We investigated type 2 diabetic patients’ data retrospectively. The data was divided as two groups (with and without diabetic peripheral neuropat...
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| Format: | Article |
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Galenos Yayincilik
2019-08-01
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| Series: | Namık Kemal Tıp Dergisi |
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http://namikkemalmedj.com/archives/archive-detail/article-preview/the-relationship-between-diabetic-peripheral-neuro/40373
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| author | Bülent BİLİR Betül EKİZ BİLİR Neslihan SOYSAL ATİLE |
| author_facet | Bülent BİLİR Betül EKİZ BİLİR Neslihan SOYSAL ATİLE |
| author_sort | Bülent BİLİR |
| collection | DOAJ |
| description | Aim:We aimed to evaluate the relationship between diabetic peripheral neuropathy and MPV values in type 2 diabetes mellitus patients.Materials and Methods:We investigated type 2 diabetic patients’ data retrospectively. The data was divided as two groups (with and without diabetic peripheral neuropathy) according to their history, physical examination, laboratory results and electro-physiological study results. The patients with cardiovascular, hematological, oncological, hepatic, renal, infectious disease or a recent history of trauma and surgery were excluded. Statistical analysis was studied by SPSS 21 soft-ware statistics programme.Results:We included 83 diabetic patients (ages between 31 and 76) that 39 of them were patients with diabetic peripheral neuropathy (25 women, 14 men) and 44(27 women, 17 men) were without neuropathy. While the means of non-neuropathic group for the age was 57,89±8,8(31-75), A1c 7,3%(5,5-12,7), platelet counts 260.800±68,900/mm3, MPV value 8,96±0,67 fl(7,6-10,4); the means of neuropathic group were 56,54±8,4(37-76) years, 8,3 (5,6-14,4)%, 269.050±74.195/mm3 and 9,03 ± 0,75(7,4-10,5) fl respectively. There were no statistically significant differences in terms of age(p=0,482), platelet count(p=0,601), body mass index(p=0,299), MPV(p=0,596) and A1c(p=0,076). But statistically significant differences were found in terms of diabetes age(p=0,002) and fasting plasma glucose(p=0,04). A statistically significant correlation was not found between MPV and neuropathy existence by Spearman correlation analysis(p=0,599).Conclusion:We didn't find any correlation between MPV value and neuropathy development in our study. We suggest that to clarify this relationship certainly, we need a prospective, multi-centered study with a bigger cohort. |
| first_indexed | 2024-04-10T11:59:04Z |
| format | Article |
| id | doaj.art-79e929059a4b4dc6951b17eb7b278109 |
| institution | Directory Open Access Journal |
| issn | 2587-0262 |
| language | English |
| last_indexed | 2024-04-10T11:59:04Z |
| publishDate | 2019-08-01 |
| publisher | Galenos Yayincilik |
| record_format | Article |
| series | Namık Kemal Tıp Dergisi |
| spelling | doaj.art-79e929059a4b4dc6951b17eb7b2781092023-02-15T16:16:41ZengGalenos YayincilikNamık Kemal Tıp Dergisi2587-02622019-08-0172727613049054The Relationship Between Diabetic Peripheral Neuropathy and (MPV) Mean Platelet Volume Values in Patients With Type 2 Diabetes MellitusBülent BİLİR0Betül EKİZ BİLİR1Neslihan SOYSAL ATİLE2 Namık Kemal Üniversitesi Tıp Fakültesi, İç Hastalıkları Ana Bilim Dalı, Tekirdağ, TÜRKİYE Tekirdağ Devlet Hastanesi, Endokrinoloji Kliniği, Tekirdağ, TÜRKİYE Nazilli Devlet Hastanesi, Endokrinoloji Kliniği, Aydın, TÜRKİYE Aim:We aimed to evaluate the relationship between diabetic peripheral neuropathy and MPV values in type 2 diabetes mellitus patients.Materials and Methods:We investigated type 2 diabetic patients’ data retrospectively. The data was divided as two groups (with and without diabetic peripheral neuropathy) according to their history, physical examination, laboratory results and electro-physiological study results. The patients with cardiovascular, hematological, oncological, hepatic, renal, infectious disease or a recent history of trauma and surgery were excluded. Statistical analysis was studied by SPSS 21 soft-ware statistics programme.Results:We included 83 diabetic patients (ages between 31 and 76) that 39 of them were patients with diabetic peripheral neuropathy (25 women, 14 men) and 44(27 women, 17 men) were without neuropathy. While the means of non-neuropathic group for the age was 57,89±8,8(31-75), A1c 7,3%(5,5-12,7), platelet counts 260.800±68,900/mm3, MPV value 8,96±0,67 fl(7,6-10,4); the means of neuropathic group were 56,54±8,4(37-76) years, 8,3 (5,6-14,4)%, 269.050±74.195/mm3 and 9,03 ± 0,75(7,4-10,5) fl respectively. There were no statistically significant differences in terms of age(p=0,482), platelet count(p=0,601), body mass index(p=0,299), MPV(p=0,596) and A1c(p=0,076). But statistically significant differences were found in terms of diabetes age(p=0,002) and fasting plasma glucose(p=0,04). A statistically significant correlation was not found between MPV and neuropathy existence by Spearman correlation analysis(p=0,599).Conclusion:We didn't find any correlation between MPV value and neuropathy development in our study. We suggest that to clarify this relationship certainly, we need a prospective, multi-centered study with a bigger cohort. http://namikkemalmedj.com/archives/archive-detail/article-preview/the-relationship-between-diabetic-peripheral-neuro/40373 diabetes mellitusdiabetic peripheral neuropathympv (mean platelet volume) |
| spellingShingle | Bülent BİLİR Betül EKİZ BİLİR Neslihan SOYSAL ATİLE The Relationship Between Diabetic Peripheral Neuropathy and (MPV) Mean Platelet Volume Values in Patients With Type 2 Diabetes Mellitus Namık Kemal Tıp Dergisi diabetes mellitus diabetic peripheral neuropathy mpv (mean platelet volume) |
| title | The Relationship Between Diabetic Peripheral Neuropathy and (MPV) Mean Platelet Volume Values in Patients With Type 2 Diabetes Mellitus |
| title_full | The Relationship Between Diabetic Peripheral Neuropathy and (MPV) Mean Platelet Volume Values in Patients With Type 2 Diabetes Mellitus |
| title_fullStr | The Relationship Between Diabetic Peripheral Neuropathy and (MPV) Mean Platelet Volume Values in Patients With Type 2 Diabetes Mellitus |
| title_full_unstemmed | The Relationship Between Diabetic Peripheral Neuropathy and (MPV) Mean Platelet Volume Values in Patients With Type 2 Diabetes Mellitus |
| title_short | The Relationship Between Diabetic Peripheral Neuropathy and (MPV) Mean Platelet Volume Values in Patients With Type 2 Diabetes Mellitus |
| title_sort | relationship between diabetic peripheral neuropathy and mpv mean platelet volume values in patients with type 2 diabetes mellitus |
| topic | diabetes mellitus diabetic peripheral neuropathy mpv (mean platelet volume) |
| url |
http://namikkemalmedj.com/archives/archive-detail/article-preview/the-relationship-between-diabetic-peripheral-neuro/40373
|
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