Post-transplant outcome-clusters of psychological distress and health-related quality of life in lung transplant recipients
QUESTIONS UNDER STUDY: To (1) assess distinct clusters of psychological distress and health-related quality of life during the first 6 months following lung transplantation; (2) identify patients with poor psychosocial outcomes; and (3) determine potential predictors regarding psychological distre...
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| Format: | Article |
| Language: | English |
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SMW supporting association (Trägerverein Swiss Medical Weekly SMW)
2015-12-01
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| Series: | Swiss Medical Weekly |
| Online Access: | https://www.smw.ch/index.php/smw/article/view/2125 |
| _version_ | 1811194161167073280 |
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| author | Annina Seiler Josef Jenewein Chantal Martin-Soelch Lutz Goetzmann Ilhan Inci Walter Weder Macé Schuurmans Christian Benden Angela Brucher Richard Klaghofer |
| author_facet | Annina Seiler Josef Jenewein Chantal Martin-Soelch Lutz Goetzmann Ilhan Inci Walter Weder Macé Schuurmans Christian Benden Angela Brucher Richard Klaghofer |
| author_sort | Annina Seiler |
| collection | DOAJ |
| description |
QUESTIONS UNDER STUDY: To (1) assess distinct clusters of psychological distress and health-related quality of life during the first 6 months following lung transplantation; (2) identify patients with poor psychosocial outcomes; and (3) determine potential predictors regarding psychological distress and health-related quality (HRQoL) of life at 6 months post-transplant.
METHODS: A total of 40 patients were examined for psychological distress (Symptom Checklist short version-9) and quality of life (EuroQOL five-dimension health-related quality of life questionnaire) during their first 6 months post-transplant. Hierarchical cluster analyses were performed to identify specific types of post-transplant outcomes in terms of psychological distress and HRQoL over the first six post-transplant months. Correlational analyses examined medical and psychosocial predictors of the outcome at 6 months post-transplant.
RESULTS: Three distinctive clusters were identified, summarizing either groups of patients with (1) optimal (35%), (2) good (42%), and (3) poor outcome-clusters (23%). The latter tended to be older, to suffer from more severe disease, to have more co-morbidities, to have had a prolonged intensive care unit and/or hospital stay, to have more hospital admissions and were more frequently treated with antidepressants post-transplant. Disease severity, length of stay, quality of life two weeks post-transplant, hospital admissions and use of antidepressants were strong predictors of psychological distress and impaired health-related quality of life at six months of follow-up.
CONCLUSION: Almost a quarter of the investigated patients suffered from elevated distress and substantially impaired HRQoL, with no improvements over time. Results underscore the psychosocial needs of patients with poor post-transplant outcomes.
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| first_indexed | 2024-04-12T00:21:17Z |
| format | Article |
| id | doaj.art-79ea53e5aed549bcb098037e95450cae |
| institution | Directory Open Access Journal |
| issn | 1424-3997 |
| language | English |
| last_indexed | 2024-04-12T00:21:17Z |
| publishDate | 2015-12-01 |
| publisher | SMW supporting association (Trägerverein Swiss Medical Weekly SMW) |
| record_format | Article |
| series | Swiss Medical Weekly |
| spelling | doaj.art-79ea53e5aed549bcb098037e95450cae2022-12-22T03:55:42ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972015-12-01145515210.4414/smw.2015.14236Post-transplant outcome-clusters of psychological distress and health-related quality of life in lung transplant recipientsAnnina SeilerJosef JeneweinChantal Martin-SoelchLutz GoetzmannIlhan InciWalter WederMacé SchuurmansChristian BendenAngela BrucherRichard Klaghofer QUESTIONS UNDER STUDY: To (1) assess distinct clusters of psychological distress and health-related quality of life during the first 6 months following lung transplantation; (2) identify patients with poor psychosocial outcomes; and (3) determine potential predictors regarding psychological distress and health-related quality (HRQoL) of life at 6 months post-transplant. METHODS: A total of 40 patients were examined for psychological distress (Symptom Checklist short version-9) and quality of life (EuroQOL five-dimension health-related quality of life questionnaire) during their first 6 months post-transplant. Hierarchical cluster analyses were performed to identify specific types of post-transplant outcomes in terms of psychological distress and HRQoL over the first six post-transplant months. Correlational analyses examined medical and psychosocial predictors of the outcome at 6 months post-transplant. RESULTS: Three distinctive clusters were identified, summarizing either groups of patients with (1) optimal (35%), (2) good (42%), and (3) poor outcome-clusters (23%). The latter tended to be older, to suffer from more severe disease, to have more co-morbidities, to have had a prolonged intensive care unit and/or hospital stay, to have more hospital admissions and were more frequently treated with antidepressants post-transplant. Disease severity, length of stay, quality of life two weeks post-transplant, hospital admissions and use of antidepressants were strong predictors of psychological distress and impaired health-related quality of life at six months of follow-up. CONCLUSION: Almost a quarter of the investigated patients suffered from elevated distress and substantially impaired HRQoL, with no improvements over time. Results underscore the psychosocial needs of patients with poor post-transplant outcomes. https://www.smw.ch/index.php/smw/article/view/2125 |
| spellingShingle | Annina Seiler Josef Jenewein Chantal Martin-Soelch Lutz Goetzmann Ilhan Inci Walter Weder Macé Schuurmans Christian Benden Angela Brucher Richard Klaghofer Post-transplant outcome-clusters of psychological distress and health-related quality of life in lung transplant recipients Swiss Medical Weekly |
| title | Post-transplant outcome-clusters of psychological distress and health-related quality of life in lung transplant recipients |
| title_full | Post-transplant outcome-clusters of psychological distress and health-related quality of life in lung transplant recipients |
| title_fullStr | Post-transplant outcome-clusters of psychological distress and health-related quality of life in lung transplant recipients |
| title_full_unstemmed | Post-transplant outcome-clusters of psychological distress and health-related quality of life in lung transplant recipients |
| title_short | Post-transplant outcome-clusters of psychological distress and health-related quality of life in lung transplant recipients |
| title_sort | post transplant outcome clusters of psychological distress and health related quality of life in lung transplant recipients |
| url | https://www.smw.ch/index.php/smw/article/view/2125 |
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