Poly-Dianix Blue/Multi-Walled Carbon Nanotube Modified Electrode for Detection of Levodopa in the Presence of High Concentrations of Ascorbic and Uric Acids
A selective and sensitive electrochemical sensor was studied for determination of levodopa (LD) in the presence of uric acid (UA) and ascorbic acid (AA) using poly-dianix blue and multi-walled carbon nanotubes (PDB/MWCNTs) modified glassy carbon electrode. Cyclic voltammetry, differential pulse volt...
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| Format: | Article |
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Slovenian Chemical Society
2017-03-01
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| Series: | Acta Chimica Slovenica |
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| Online Access: | https://journals.matheo.si/index.php/ACSi/article/view/3097 |
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| author | Abdolhamid Hatefi-Mehrjardi Mohammad Ali Karimi Azam Barani Mahdiyeh Soleymanzadeh |
| author_facet | Abdolhamid Hatefi-Mehrjardi Mohammad Ali Karimi Azam Barani Mahdiyeh Soleymanzadeh |
| author_sort | Abdolhamid Hatefi-Mehrjardi |
| collection | DOAJ |
| description | A selective and sensitive electrochemical sensor was studied for determination of levodopa (LD) in the presence of uric acid (UA) and ascorbic acid (AA) using poly-dianix blue and multi-walled carbon nanotubes (PDB/MWCNTs) modified glassy carbon electrode. Cyclic voltammetry, differential pulse voltammetry, and chronoamperometry methods were applied to investigate the electrocatalytic oxidation of LD, UA and AA in aqueous solutions. By DPV technique, LD, UA and AA give oxidation peaks at 0.380, 0.520 and 0.180 V, respectively. Under the optimized experimental conditions LD, UA and AA give a linear response in the range of 0.09‑75 µmol L-1, 0.3–110 µmol L-1 and 10–160 µmol L-1, respectively. Accordingly, the obtained detection limits were 0.003, 0.002 and 0.023 µmol L‑1. The method provides a simple electrochemical sensor for successful determination of LD in human blood serum samples. |
| first_indexed | 2024-04-13T02:28:34Z |
| format | Article |
| id | doaj.art-79ec22420bd44936bb2c2d5121d278bf |
| institution | Directory Open Access Journal |
| issn | 1318-0207 1580-3155 |
| language | English |
| last_indexed | 2024-04-13T02:28:34Z |
| publishDate | 2017-03-01 |
| publisher | Slovenian Chemical Society |
| record_format | Article |
| series | Acta Chimica Slovenica |
| spelling | doaj.art-79ec22420bd44936bb2c2d5121d278bf2022-12-22T03:06:40ZengSlovenian Chemical SocietyActa Chimica Slovenica1318-02071580-31552017-03-0164119320110.17344/acsi.2016.3097438Poly-Dianix Blue/Multi-Walled Carbon Nanotube Modified Electrode for Detection of Levodopa in the Presence of High Concentrations of Ascorbic and Uric AcidsAbdolhamid Hatefi-Mehrjardi0Mohammad Ali Karimi1Azam Barani2Mahdiyeh Soleymanzadeh3Department of Chemistry, Payame Noor University, 19395-3697, Tehran, IranDepartment of Chemistry, Payame Noor University, 19395-3697, Tehran, IranDepartment of Chemistry & Nanoscience and Nanotechnology Research Laboratory (NNRL), Payame Noor University (PNU), Sirjan, IranDepartment of Chemistry & Nanoscience and Nanotechnology Research Laboratory (NNRL), Payame Noor University (PNU), Sirjan, IranA selective and sensitive electrochemical sensor was studied for determination of levodopa (LD) in the presence of uric acid (UA) and ascorbic acid (AA) using poly-dianix blue and multi-walled carbon nanotubes (PDB/MWCNTs) modified glassy carbon electrode. Cyclic voltammetry, differential pulse voltammetry, and chronoamperometry methods were applied to investigate the electrocatalytic oxidation of LD, UA and AA in aqueous solutions. By DPV technique, LD, UA and AA give oxidation peaks at 0.380, 0.520 and 0.180 V, respectively. Under the optimized experimental conditions LD, UA and AA give a linear response in the range of 0.09‑75 µmol L-1, 0.3–110 µmol L-1 and 10–160 µmol L-1, respectively. Accordingly, the obtained detection limits were 0.003, 0.002 and 0.023 µmol L‑1. The method provides a simple electrochemical sensor for successful determination of LD in human blood serum samples.https://journals.matheo.si/index.php/ACSi/article/view/3097Dianix BlueCarbon NanotubesModified ElectrodeLevodopaUric AcidAscorbic Acid. |
| spellingShingle | Abdolhamid Hatefi-Mehrjardi Mohammad Ali Karimi Azam Barani Mahdiyeh Soleymanzadeh Poly-Dianix Blue/Multi-Walled Carbon Nanotube Modified Electrode for Detection of Levodopa in the Presence of High Concentrations of Ascorbic and Uric Acids Acta Chimica Slovenica Dianix Blue Carbon Nanotubes Modified Electrode Levodopa Uric Acid Ascorbic Acid. |
| title | Poly-Dianix Blue/Multi-Walled Carbon Nanotube Modified Electrode for Detection of Levodopa in the Presence of High Concentrations of Ascorbic and Uric Acids |
| title_full | Poly-Dianix Blue/Multi-Walled Carbon Nanotube Modified Electrode for Detection of Levodopa in the Presence of High Concentrations of Ascorbic and Uric Acids |
| title_fullStr | Poly-Dianix Blue/Multi-Walled Carbon Nanotube Modified Electrode for Detection of Levodopa in the Presence of High Concentrations of Ascorbic and Uric Acids |
| title_full_unstemmed | Poly-Dianix Blue/Multi-Walled Carbon Nanotube Modified Electrode for Detection of Levodopa in the Presence of High Concentrations of Ascorbic and Uric Acids |
| title_short | Poly-Dianix Blue/Multi-Walled Carbon Nanotube Modified Electrode for Detection of Levodopa in the Presence of High Concentrations of Ascorbic and Uric Acids |
| title_sort | poly dianix blue multi walled carbon nanotube modified electrode for detection of levodopa in the presence of high concentrations of ascorbic and uric acids |
| topic | Dianix Blue Carbon Nanotubes Modified Electrode Levodopa Uric Acid Ascorbic Acid. |
| url | https://journals.matheo.si/index.php/ACSi/article/view/3097 |
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