Inhibitory Effects of Diclofenac on Steroid Glucuronidation In Vivo Do Not Affect Hair-Based Doping Tests for Stanozolol

Inhibitory Effects of Diclofenac on Steroid Glucuronidation In Vivo Do Not Affect Hair-Based Doping Tests for Stanozolol

In vitro studies show that diclofenac inhibits enzymatic steroid glucuronidation. This study was designed to investigate the influence of diclofenac on the excretion of stanozolol and 3′-hydroxystanozolol via analyses in hair, blood and urine in vivo in a rat study. Brown Norway rats were administer...

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Bibliographic Details
Main Authors: Gergely Zachár, Naved I.K. Deshmukh, Andrea Petróczi, Andrea D. Székely, Iltaf Shah, James Barker, Declan P. Naughton
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Molecules
Subjects:
steroid
metabolism
anti-inflammatory drug
inhibition
Online Access:http://www.mdpi.com/1420-3049/22/6/976

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