Global gene analysis identifying genes commonly regulated by the Ras/Raf/MEK and type I IFN pathways

Global gene analysis identifying genes commonly regulated by the Ras/Raf/MEK and type I IFN pathways

Oncolytic viruses exploit alterations in cancer cells to specifically infect cancer cells but not normal healthy cells. Previous work has shown that oncogenic Ras interferes with interferon (IFN) signaling to promote viral replication. Furthermore, inhibition of the Ras/Raf/MEK/ERK pathway at the le...

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Bibliographic Details
Main Authors: Y. Komatsu, K. Hirasawa, S.L. Christian
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Genomics Data
Subjects:
Oncogenic Ras
Ras/Raf/MEK
U0126
Type I interferon
NIH/3T3
Online Access:http://www.sciencedirect.com/science/article/pii/S221359601500029X

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