Development of a Novel Dorsal Incision Only Invagination Type Pancreatogastrostomy (Charité-PG) Following Open Pancreaticoduodenectomy—A Single Centre Experience
The implementation of a pancreatico-enteric anastomosis following open single stage pancreaticoduodenectomy (PD) is still associated with the most threatening complications in modern pancreatic surgery, such as postoperative pancreatic fistula (POPF), postpancreatectomy haemorrhage (PPH), delayed ga...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/12/2573 |
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| author | Lea Timmermann Marcus Bahra Johann Pratschke Thomas Malinka |
| author_facet | Lea Timmermann Marcus Bahra Johann Pratschke Thomas Malinka |
| author_sort | Lea Timmermann |
| collection | DOAJ |
| description | The implementation of a pancreatico-enteric anastomosis following open single stage pancreaticoduodenectomy (PD) is still associated with the most threatening complications in modern pancreatic surgery, such as postoperative pancreatic fistula (POPF), postpancreatectomy haemorrhage (PPH), delayed gastric emptying (DGE), intraabdominal abscesses and related mortality. With this study, we introduce Charité-PG, a new dorsal incision only invagination type pancreatogastrostomy (dioPG) for the restoration of the pancreatic remnant following PD, and compare it to a PG requiring ventral gastrotomy (vgPG). A total of 49 consecutive patients, who underwent reconstruction via dioPG, and 92 consecutive patients, who underwent restoration via vgPG, were identified from our prospective database and further reviewed for perioperative parameters, complication rates, mortality and follow-up. The percentage of overall complications (<i>p</i> = 0.301), as well as the 30-day mortality rate (<i>p</i> = 0.725) and survival (<i>p</i> = 0.543), were comparable in both groups. The operation time in the dioPG group was significantly shorter (<i>p</i> = 0.04), and patients in this group developed substantially fewer rates of DGE (<i>p</i> = 0.036). We provide a feasible and safe technique for restoration following PD via our novel dioPG, causing fewer cases of DGE. Nevertheless, pancreatico-enteric anastomoses require expertise and experience. |
| first_indexed | 2024-03-10T10:31:20Z |
| format | Article |
| id | doaj.art-79f152d8cfca4883b8c54f2c7984fc67 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T10:31:20Z |
| publishDate | 2021-06-01 |
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| series | Journal of Clinical Medicine |
| spelling | doaj.art-79f152d8cfca4883b8c54f2c7984fc672023-11-21T23:36:54ZengMDPI AGJournal of Clinical Medicine2077-03832021-06-011012257310.3390/jcm10122573Development of a Novel Dorsal Incision Only Invagination Type Pancreatogastrostomy (Charité-PG) Following Open Pancreaticoduodenectomy—A Single Centre ExperienceLea Timmermann0Marcus Bahra1Johann Pratschke2Thomas Malinka3Department of Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 14195 Berlin, GermanyDepartment of Oncological Upper Abdominal Surgery and Robotic- Krankenhaus Waldfriede, 14163 Berlin, GermanyDepartment of Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 14195 Berlin, GermanyDepartment of Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 14195 Berlin, GermanyThe implementation of a pancreatico-enteric anastomosis following open single stage pancreaticoduodenectomy (PD) is still associated with the most threatening complications in modern pancreatic surgery, such as postoperative pancreatic fistula (POPF), postpancreatectomy haemorrhage (PPH), delayed gastric emptying (DGE), intraabdominal abscesses and related mortality. With this study, we introduce Charité-PG, a new dorsal incision only invagination type pancreatogastrostomy (dioPG) for the restoration of the pancreatic remnant following PD, and compare it to a PG requiring ventral gastrotomy (vgPG). A total of 49 consecutive patients, who underwent reconstruction via dioPG, and 92 consecutive patients, who underwent restoration via vgPG, were identified from our prospective database and further reviewed for perioperative parameters, complication rates, mortality and follow-up. The percentage of overall complications (<i>p</i> = 0.301), as well as the 30-day mortality rate (<i>p</i> = 0.725) and survival (<i>p</i> = 0.543), were comparable in both groups. The operation time in the dioPG group was significantly shorter (<i>p</i> = 0.04), and patients in this group developed substantially fewer rates of DGE (<i>p</i> = 0.036). We provide a feasible and safe technique for restoration following PD via our novel dioPG, causing fewer cases of DGE. Nevertheless, pancreatico-enteric anastomoses require expertise and experience.https://www.mdpi.com/2077-0383/10/12/2573pancreatogastrostomypancreato-enteric anastomosispancreaticoduodenectomy |
| spellingShingle | Lea Timmermann Marcus Bahra Johann Pratschke Thomas Malinka Development of a Novel Dorsal Incision Only Invagination Type Pancreatogastrostomy (Charité-PG) Following Open Pancreaticoduodenectomy—A Single Centre Experience Journal of Clinical Medicine pancreatogastrostomy pancreato-enteric anastomosis pancreaticoduodenectomy |
| title | Development of a Novel Dorsal Incision Only Invagination Type Pancreatogastrostomy (Charité-PG) Following Open Pancreaticoduodenectomy—A Single Centre Experience |
| title_full | Development of a Novel Dorsal Incision Only Invagination Type Pancreatogastrostomy (Charité-PG) Following Open Pancreaticoduodenectomy—A Single Centre Experience |
| title_fullStr | Development of a Novel Dorsal Incision Only Invagination Type Pancreatogastrostomy (Charité-PG) Following Open Pancreaticoduodenectomy—A Single Centre Experience |
| title_full_unstemmed | Development of a Novel Dorsal Incision Only Invagination Type Pancreatogastrostomy (Charité-PG) Following Open Pancreaticoduodenectomy—A Single Centre Experience |
| title_short | Development of a Novel Dorsal Incision Only Invagination Type Pancreatogastrostomy (Charité-PG) Following Open Pancreaticoduodenectomy—A Single Centre Experience |
| title_sort | development of a novel dorsal incision only invagination type pancreatogastrostomy charite pg following open pancreaticoduodenectomy a single centre experience |
| topic | pancreatogastrostomy pancreato-enteric anastomosis pancreaticoduodenectomy |
| url | https://www.mdpi.com/2077-0383/10/12/2573 |
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