NOVOSIBIRSK REGION PROGRAM OF THE LIVER TRANSPLANTATION IN CHILDREN
The aim of the study was to analyze the early and late outcomes of pediatric liver transplantation (LTx) program in the Novosibirsk region. Material and Methods. The retrospective study included 24 patients aged 72 ± 74.8 months (from 4 to 212 months, median – 20 months) with a body weight of 21.7 ±...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Russian Academy of Sciences, Siberian Branch Publishing House
2020-03-01
|
| Series: | Сибирский научный медицинский журнал |
| Subjects: | |
| Online Access: | https://sibmed.elpub.ru/jour/article/view/333 |
| _version_ | 1826575766964404224 |
|---|---|
| author | I. A. Porshennikov A. Yu. Bykov M. A. Korobeynikova E. G. Yushina V. N. Pavlik E. E. Shchekina K. Yu. Beloborodov K. A. Gryaznov S. V. Danchenko A. B. Nikulina I. G. Grinberg E. I. Streltsova A. V. Yudanov |
| author_facet | I. A. Porshennikov A. Yu. Bykov M. A. Korobeynikova E. G. Yushina V. N. Pavlik E. E. Shchekina K. Yu. Beloborodov K. A. Gryaznov S. V. Danchenko A. B. Nikulina I. G. Grinberg E. I. Streltsova A. V. Yudanov |
| author_sort | I. A. Porshennikov |
| collection | DOAJ |
| description | The aim of the study was to analyze the early and late outcomes of pediatric liver transplantation (LTx) program in the Novosibirsk region. Material and Methods. The retrospective study included 24 patients aged 72 ± 74.8 months (from 4 to 212 months, median – 20 months) with a body weight of 21.7 ± 18.1 kg (from 4.5 to 55 kg, median – 12.5 kg). Two (8.3 %) cadaveric whole liver grafts, 19 (79.2 %) living donor liver grafts, and 3 (12.5 %) cadaveric liver fragments (reduced-size or split-liver) were transplanted. Results. The features of vascular and biliary reconstruction in different types of LTx are discussed. The incidence of vascular and biliary complications was 8.3 and 20.8%, respectively. The patients stayed in the intensive care unit for 9 ± 5.1 days (from 4 to 22 days, median 8 days) and total length of hospital stay was for 40 ± 25.4 days (from 19 to 136 days, median 32 days). Two (8.3 %) recipients had early graft dysfunction. Perioperative mortality (up to 90 days) was absent. The overall 5-year patient and graft survival rates were 95 and 88 %, respectively. Conclusion. The Novosibirsk region has a pediatric LTx program with outcomes comparable to the data of the leading world and Russian centers. |
| first_indexed | 2024-03-08T14:34:05Z |
| format | Article |
| id | doaj.art-79f1f4c138264a4492516439de8ba6f2 |
| institution | Directory Open Access Journal |
| issn | 2410-2512 2410-2520 |
| language | Russian |
| last_indexed | 2025-03-14T13:19:55Z |
| publishDate | 2020-03-01 |
| publisher | Russian Academy of Sciences, Siberian Branch Publishing House |
| record_format | Article |
| series | Сибирский научный медицинский журнал |
| spelling | doaj.art-79f1f4c138264a4492516439de8ba6f22025-02-28T13:43:55ZrusRussian Academy of Sciences, Siberian Branch Publishing HouseСибирский научный медицинский журнал2410-25122410-25202020-03-01401203010.15372/SSMJ20200103230NOVOSIBIRSK REGION PROGRAM OF THE LIVER TRANSPLANTATION IN CHILDRENI. A. Porshennikov0A. Yu. Bykov1M. A. Korobeynikova2E. G. Yushina3V. N. Pavlik4E. E. Shchekina5K. Yu. Beloborodov6K. A. Gryaznov7S. V. Danchenko8A. B. Nikulina9I. G. Grinberg10E. I. Streltsova11A. V. Yudanov12State Novosibirsk Regional Clinical Hospital, Novosibirsk State Medical University of Minzdrav of RussiaNovosibirsk State Medical University of Minzdrav of RussiaState Novosibirsk Regional Clinical HospitalState Novosibirsk Regional Clinical HospitalState Novosibirsk Regional Clinical HospitalState Novosibirsk Regional Clinical HospitalState Novosibirsk Regional Clinical HospitalState Novosibirsk Regional Clinical HospitalState Novosibirsk Regional Clinical HospitalState Novosibirsk Regional Clinical Hospital, Novosibirsk State Medical University of Minzdrav of RussiaState Novosibirsk Regional Clinical HospitalState Novosibirsk Regional Clinical Hospital, Novosibirsk State Medical University of Minzdrav of RussiaState Novosibirsk Regional Clinical Hospital, Novosibirsk State Medical University of Minzdrav of RussiaThe aim of the study was to analyze the early and late outcomes of pediatric liver transplantation (LTx) program in the Novosibirsk region. Material and Methods. The retrospective study included 24 patients aged 72 ± 74.8 months (from 4 to 212 months, median – 20 months) with a body weight of 21.7 ± 18.1 kg (from 4.5 to 55 kg, median – 12.5 kg). Two (8.3 %) cadaveric whole liver grafts, 19 (79.2 %) living donor liver grafts, and 3 (12.5 %) cadaveric liver fragments (reduced-size or split-liver) were transplanted. Results. The features of vascular and biliary reconstruction in different types of LTx are discussed. The incidence of vascular and biliary complications was 8.3 and 20.8%, respectively. The patients stayed in the intensive care unit for 9 ± 5.1 days (from 4 to 22 days, median 8 days) and total length of hospital stay was for 40 ± 25.4 days (from 19 to 136 days, median 32 days). Two (8.3 %) recipients had early graft dysfunction. Perioperative mortality (up to 90 days) was absent. The overall 5-year patient and graft survival rates were 95 and 88 %, respectively. Conclusion. The Novosibirsk region has a pediatric LTx program with outcomes comparable to the data of the leading world and Russian centers.https://sibmed.elpub.ru/jour/article/view/333liver transplantation in childrenpediatric liver transplantationleft lateral section liver transplantationliving-related donor liver transplantationliver transplantation outcomes |
| spellingShingle | I. A. Porshennikov A. Yu. Bykov M. A. Korobeynikova E. G. Yushina V. N. Pavlik E. E. Shchekina K. Yu. Beloborodov K. A. Gryaznov S. V. Danchenko A. B. Nikulina I. G. Grinberg E. I. Streltsova A. V. Yudanov NOVOSIBIRSK REGION PROGRAM OF THE LIVER TRANSPLANTATION IN CHILDREN Сибирский научный медицинский журнал liver transplantation in children pediatric liver transplantation left lateral section liver transplantation living-related donor liver transplantation liver transplantation outcomes |
| title | NOVOSIBIRSK REGION PROGRAM OF THE LIVER TRANSPLANTATION IN CHILDREN |
| title_full | NOVOSIBIRSK REGION PROGRAM OF THE LIVER TRANSPLANTATION IN CHILDREN |
| title_fullStr | NOVOSIBIRSK REGION PROGRAM OF THE LIVER TRANSPLANTATION IN CHILDREN |
| title_full_unstemmed | NOVOSIBIRSK REGION PROGRAM OF THE LIVER TRANSPLANTATION IN CHILDREN |
| title_short | NOVOSIBIRSK REGION PROGRAM OF THE LIVER TRANSPLANTATION IN CHILDREN |
| title_sort | novosibirsk region program of the liver transplantation in children |
| topic | liver transplantation in children pediatric liver transplantation left lateral section liver transplantation living-related donor liver transplantation liver transplantation outcomes |
| url | https://sibmed.elpub.ru/jour/article/view/333 |
| work_keys_str_mv | AT iaporshennikov novosibirskregionprogramofthelivertransplantationinchildren AT ayubykov novosibirskregionprogramofthelivertransplantationinchildren AT makorobeynikova novosibirskregionprogramofthelivertransplantationinchildren AT egyushina novosibirskregionprogramofthelivertransplantationinchildren AT vnpavlik novosibirskregionprogramofthelivertransplantationinchildren AT eeshchekina novosibirskregionprogramofthelivertransplantationinchildren AT kyubeloborodov novosibirskregionprogramofthelivertransplantationinchildren AT kagryaznov novosibirskregionprogramofthelivertransplantationinchildren AT svdanchenko novosibirskregionprogramofthelivertransplantationinchildren AT abnikulina novosibirskregionprogramofthelivertransplantationinchildren AT iggrinberg novosibirskregionprogramofthelivertransplantationinchildren AT eistreltsova novosibirskregionprogramofthelivertransplantationinchildren AT avyudanov novosibirskregionprogramofthelivertransplantationinchildren |