Targeting TRPV1 activity via high‐dose capsaicin in patients with sickle cell disease

Targeting TRPV1 activity via high‐dose capsaicin in patients with sickle cell disease

Abstract Evidence suggests neuropathic pain (NP) develops over time in sickle cell disease (SCD), contributing to a complex, difficult‐to‐treat phenotype, with management based on scant evidence. One characteristic of NP found is hyperalgesia caused by nervous system sensitization, but risk factors...

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Bibliographic Details
Main Authors:	Alexander K. Glaros, Michael U. Callaghan, Wally R. Smith, Ahmar U. Zaidi
Format:	Article
Language:	English
Published:	Wiley 2022-08-01
Series:	eJHaem
Subjects:	capsaicin chronic pain neuropathic pain quantitative sensory testing sickle cell disease
Online Access:	https://doi.org/10.1002/jha2.528

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