Monocarboxylate Transporter 4 Regulates Glioblastoma Motility and Monocyte Binding Ability

Monocarboxylate Transporter 4 Regulates Glioblastoma Motility and Monocyte Binding Ability

Glioblastoma (GBM) is characterized by severe hypoxic and acidic stress in an abnormal microenvironment. Monocarboxylate transporter (MCT)4, a pH-regulating protein, plays an important role in pH homeostasis of the glycolytic metabolic pathways in cancer cells. The present study showed that GBM expo...

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Bibliographic Details
Main Authors: Sheng-Wei Lai, Hui-Jung Lin, Yu-Shu Liu, Liang-Yo Yang, Dah-Yuu Lu
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
glioblastoma
hypoxic conditions
acidic microenvironment
mct4
monocytes
Online Access:https://www.mdpi.com/2072-6694/12/2/380

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