Coronary pathology in patients after chest radiotherapy

Radiation therapy is the main treatment for a large number of neoplastic diseases. Improved survival in this group of patients led to the emergence of a new nosological unit – radiation-induced damage to neighbouring organs and systems. Data accumulated in recent decades has proven conclusively that...

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Main Authors: Denislav Biserov, Ivaneta Yoncheva, Mariana Konteva, Svetoslav Gogov
Format: Article
Language:Bulgarian
Published: Pensoft Publishers 2021-07-01
Series:Българска кардиология
Subjects:
Online Access:https://journal.bgcardio.org/article/60233/download/pdf/
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author Denislav Biserov
Ivaneta Yoncheva
Mariana Konteva
Svetoslav Gogov
author_facet Denislav Biserov
Ivaneta Yoncheva
Mariana Konteva
Svetoslav Gogov
author_sort Denislav Biserov
collection DOAJ
description Radiation therapy is the main treatment for a large number of neoplastic diseases. Improved survival in this group of patients led to the emergence of a new nosological unit – radiation-induced damage to neighbouring organs and systems. Data accumulated in recent decades has proven conclusively that chest radiotherapy could result in heart damage. Cardiovascular diseases are the leading cause of death in oncological patients in remission. The onset of radiation-induced heart disease (RIHD) can be early with clinical picture of acute myocarditis and late with manifestations of constrictive pericarditis, restrictive cardiomyopathy, coronary artery disease, valvular involvement, heart failure and conduction pathology. Clinical symptoms may manifest years after exposure to radiation. Our team performed a mini-review on the topic, after which we shared our own experience in 10 patients who underwent radiation therapy in the past and were admitted to the Clinic of Cardiology of University Multyprofile Hospital for Active Treatment „Deva Mariya“ with a clinical picture of ACS.
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spelling doaj.art-79fdfcbd87a74e90865a82a5047e73de2023-12-02T14:33:00ZbulPensoft PublishersБългарска кардиология2683-10152021-07-01272788310.3897/bgcardio.27.e6023360233Coronary pathology in patients after chest radiotherapyDenislav Biserov0Ivaneta Yoncheva1Mariana Konteva2Svetoslav Gogov3University Hospital Virgin MaryUniversity Hospital Virgin MaryUniversity Hospital Virgin MaryUniversity Hospital Virgin MaryRadiation therapy is the main treatment for a large number of neoplastic diseases. Improved survival in this group of patients led to the emergence of a new nosological unit – radiation-induced damage to neighbouring organs and systems. Data accumulated in recent decades has proven conclusively that chest radiotherapy could result in heart damage. Cardiovascular diseases are the leading cause of death in oncological patients in remission. The onset of radiation-induced heart disease (RIHD) can be early with clinical picture of acute myocarditis and late with manifestations of constrictive pericarditis, restrictive cardiomyopathy, coronary artery disease, valvular involvement, heart failure and conduction pathology. Clinical symptoms may manifest years after exposure to radiation. Our team performed a mini-review on the topic, after which we shared our own experience in 10 patients who underwent radiation therapy in the past and were admitted to the Clinic of Cardiology of University Multyprofile Hospital for Active Treatment „Deva Mariya“ with a clinical picture of ACS.https://journal.bgcardio.org/article/60233/download/pdf/breast cancerradiation therapyacute coronary e
spellingShingle Denislav Biserov
Ivaneta Yoncheva
Mariana Konteva
Svetoslav Gogov
Coronary pathology in patients after chest radiotherapy
Българска кардиология
breast cancer
radiation therapy
acute coronary e
title Coronary pathology in patients after chest radiotherapy
title_full Coronary pathology in patients after chest radiotherapy
title_fullStr Coronary pathology in patients after chest radiotherapy
title_full_unstemmed Coronary pathology in patients after chest radiotherapy
title_short Coronary pathology in patients after chest radiotherapy
title_sort coronary pathology in patients after chest radiotherapy
topic breast cancer
radiation therapy
acute coronary e
url https://journal.bgcardio.org/article/60233/download/pdf/
work_keys_str_mv AT denislavbiserov coronarypathologyinpatientsafterchestradiotherapy
AT ivanetayoncheva coronarypathologyinpatientsafterchestradiotherapy
AT marianakonteva coronarypathologyinpatientsafterchestradiotherapy
AT svetoslavgogov coronarypathologyinpatientsafterchestradiotherapy