Evolution of Microbial Flora Colonizing Burn Wounds during Hospitalization in Uruguay
(1) Background: Infections are a main cause of morbidity and mortality among burn patients. The spectrum of microorganisms depends on the epidemiological context and treatment practices. We aimed to describe the evolution of microbial flora colonizing burn wounds among patients hospitalized during 1...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/11/11/2900 |
| _version_ | 1797460051169902592 |
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| author | Marina Macedo-Viñas Andrea Lucas |
| author_facet | Marina Macedo-Viñas Andrea Lucas |
| author_sort | Marina Macedo-Viñas |
| collection | DOAJ |
| description | (1) Background: Infections are a main cause of morbidity and mortality among burn patients. The spectrum of microorganisms depends on the epidemiological context and treatment practices. We aimed to describe the evolution of microbial flora colonizing burn wounds among patients hospitalized during 15 or more days at the National Burn Center in 2015. (2) Methods: Demographic data, length of stay, total body surface area burn, and status at discharge were collected from electronic records and culture results from the laboratory database. (3) Results: Among 98 included patients, 87 were colonized. The mean length of stay was 39 days overall and 16 days in the ICU. <i>Acinetobacter</i> spp., <i>Enterococcus</i> spp., and <i>Staphylococcus aureus</i> predominated. Fifty-six patients harbored multidrug-resistant bacteria and had a significantly greater TBSA. The mean time to colonization was 6 days overall and 14 days for multidrug-resistant bacteria; it was significantly longer for methicillin-resistant <i>S. aureus</i> than for methicillin-susceptible <i>S. aureus</i>. (4) Conclusions: This is the first report describing the dynamics of microbial colonization of burn wounds in Uruguay. Similarities were found with reports elsewhere, but early colonization with yeasts and the absence of <i>Streptococcus pyogenes</i> were unique. Each burn center needs to monitor its microbial ecology to tailor their antimicrobial strategies effectively. |
| first_indexed | 2024-03-09T17:00:40Z |
| format | Article |
| id | doaj.art-7a00888ddc564ef79f1499ecfce273ae |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-09T17:00:40Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-7a00888ddc564ef79f1499ecfce273ae2023-11-24T14:30:38ZengMDPI AGBiomedicines2227-90592023-10-011111290010.3390/biomedicines11112900Evolution of Microbial Flora Colonizing Burn Wounds during Hospitalization in UruguayMarina Macedo-Viñas0Andrea Lucas1Centro Nacional de Quemados, Hospital de Clínicas, Piso 13, Avenida Italia s/n, Montevideo 11600, UruguayCentro Nacional de Quemados, Hospital de Clínicas, Piso 13, Avenida Italia s/n, Montevideo 11600, Uruguay(1) Background: Infections are a main cause of morbidity and mortality among burn patients. The spectrum of microorganisms depends on the epidemiological context and treatment practices. We aimed to describe the evolution of microbial flora colonizing burn wounds among patients hospitalized during 15 or more days at the National Burn Center in 2015. (2) Methods: Demographic data, length of stay, total body surface area burn, and status at discharge were collected from electronic records and culture results from the laboratory database. (3) Results: Among 98 included patients, 87 were colonized. The mean length of stay was 39 days overall and 16 days in the ICU. <i>Acinetobacter</i> spp., <i>Enterococcus</i> spp., and <i>Staphylococcus aureus</i> predominated. Fifty-six patients harbored multidrug-resistant bacteria and had a significantly greater TBSA. The mean time to colonization was 6 days overall and 14 days for multidrug-resistant bacteria; it was significantly longer for methicillin-resistant <i>S. aureus</i> than for methicillin-susceptible <i>S. aureus</i>. (4) Conclusions: This is the first report describing the dynamics of microbial colonization of burn wounds in Uruguay. Similarities were found with reports elsewhere, but early colonization with yeasts and the absence of <i>Streptococcus pyogenes</i> were unique. Each burn center needs to monitor its microbial ecology to tailor their antimicrobial strategies effectively.https://www.mdpi.com/2227-9059/11/11/2900burnsmicrobial epidemiologywound colonizationantibiotic resistance |
| spellingShingle | Marina Macedo-Viñas Andrea Lucas Evolution of Microbial Flora Colonizing Burn Wounds during Hospitalization in Uruguay Biomedicines burns microbial epidemiology wound colonization antibiotic resistance |
| title | Evolution of Microbial Flora Colonizing Burn Wounds during Hospitalization in Uruguay |
| title_full | Evolution of Microbial Flora Colonizing Burn Wounds during Hospitalization in Uruguay |
| title_fullStr | Evolution of Microbial Flora Colonizing Burn Wounds during Hospitalization in Uruguay |
| title_full_unstemmed | Evolution of Microbial Flora Colonizing Burn Wounds during Hospitalization in Uruguay |
| title_short | Evolution of Microbial Flora Colonizing Burn Wounds during Hospitalization in Uruguay |
| title_sort | evolution of microbial flora colonizing burn wounds during hospitalization in uruguay |
| topic | burns microbial epidemiology wound colonization antibiotic resistance |
| url | https://www.mdpi.com/2227-9059/11/11/2900 |
| work_keys_str_mv | AT marinamacedovinas evolutionofmicrobialfloracolonizingburnwoundsduringhospitalizationinuruguay AT andrealucas evolutionofmicrobialfloracolonizingburnwoundsduringhospitalizationinuruguay |