The Role of VHL in the Development of von Hippel-Lindau Disease and Erythrocytosis

The Role of VHL in the Development of von Hippel-Lindau Disease and Erythrocytosis

Von Hippel-Lindau disease (VHL disease or VHL syndrome) is a familial multisystem neoplastic syndrome stemming from germline disease-associated variants of the <i>VHL</i> tumor suppressor gene on chromosome 3. VHL is involved, through the EPO-VHL-HIF signaling axis, in oxygen sensing and...

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Bibliographic Details
Main Authors:	Petra Hudler, Mojca Urbancic
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	Genes
Subjects:	VHL VHL disease Chuvash polycythemia genetic variation erythrocytosis pheochromocytoma
Online Access:	https://www.mdpi.com/2073-4425/13/2/362

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