GUIP1: a R package for dose escalation strategies in phase I cancer clinical trials

GUIP1: a R package for dose escalation strategies in phase I cancer clinical trials

Abstract Background The main objective of phase I cancer clinical trials is to identify the maximum tolerated dose, usually defined as the highest dose associated with an acceptable level of severe toxicity during the first cycle of treatment. Several dose-escalation designs based on mathematical mo...

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Bibliographic Details
Main Authors: D. Dinart, J. Fraisse, D. Tosi, A. Mauguen, C. Touraine, S. Gourgou, M. C. Le Deley, C. Bellera, C. Mollevi
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Medical Informatics and Decision Making
Subjects:
Phase 1 clinical trial
Graphical user interface
Dose escalation design
Online Access:http://link.springer.com/article/10.1186/s12911-020-01149-3

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