Role of mi-RNAs in Respiratory Diseases

Ever since the initial discovery in the early 1990s, microRNAs have become the focus of a multitude of conditions from basic biology to clinical applications in both diagnostic and prognostic strata. Previously they were believed to be of no biological relevance. Even in diseases of the lung, microR...

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Bibliographic Details
Main Authors: R Vimal Raj, R Pajanivel
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Journal of Association of Pulmonologist of Tamil Nadu
Subjects:
Online Access:http://www.japt.in/article.asp?issn=2772-6355;year=2018;volume=1;issue=2;spage=64;epage=67;aulast=Raj;type=0
Description
Summary:Ever since the initial discovery in the early 1990s, microRNAs have become the focus of a multitude of conditions from basic biology to clinical applications in both diagnostic and prognostic strata. Previously they were believed to be of no biological relevance. Even in diseases of the lung, microRNAs have been analyzed in the pathophysiology, as drivers of disease, potential treatment targets, and serum biomarkers; however, much is yet to be understood about these non-coding RNAs for us to fully realize their potential therapeutic use. Here, we give a brief insight into their role in major respiratory diseases unearthed so far and the road ahead to better understand this potential biomarker.
ISSN:2772-6355
2772-6363