Willingness to test for BRCA1/2 in high risk women: Influenced by risk perception and family experience, rather than by objective or subjective numeracy?
Genetic testing for breast and ovarian cancer can help target prevention programs, and possibly reduce morbidity and mortality. A positive result of BRCA1/2 is a substantial risk factor for breast and ovarian cancer, and its detection often leads to risk reduction interventions such as increased scr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2015-07-01
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| Series: | Judgment and Decision Making |
| Subjects: | |
| Online Access: | http://journal.sjdm.org/15/15201/jdm15201.pdf |
| _version_ | 1797705128970551296 |
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| author | Talya Miron-Shatz Yaniv Hanoch Benjamin A. Katz Glen M. Doniger Elissa M. Ozanne |
| author_facet | Talya Miron-Shatz Yaniv Hanoch Benjamin A. Katz Glen M. Doniger Elissa M. Ozanne |
| author_sort | Talya Miron-Shatz |
| collection | DOAJ |
| description | Genetic testing for
breast and ovarian cancer can help target prevention programs, and possibly
reduce morbidity and mortality. A positive result of BRCA1/2 is a substantial
risk factor for breast and ovarian cancer, and its detection often leads to
risk reduction interventions such as increased screening, prophylactic
mastectomy and oophorectomy. We examined predictors of the decision to undergo
cancer related genetic testing: perceived risk, family risk of breast or
ovarian cancer, and numeracy as predictors of the decision to test among women
at high risk of breast cancer. Stepwise regression analysis of survey responses
from 459 women registered in the Cancer Genetics Network revealed greater
likelihood to test for women with more family history, higher perceived risk of
mutation, or Ashkenazi descent. Neither subjective nor objective numeracy was
associated with the decision to test, although we replicated an earlier finding
that subjective numeracy predicted willingness to pay for testing. Findings
underscore the need for genetic counselling that disentangles risk perception
from objective information to promote better decision-making in the context of
genetic testing. Highlighting these factors is crucial for public health
campaigns, as well as to clinic-based testing and direct-to-consumer
testing. |
| first_indexed | 2024-03-12T05:32:33Z |
| format | Article |
| id | doaj.art-7a0e049bc8cc450dacf5faa8292194e5 |
| institution | Directory Open Access Journal |
| issn | 1930-2975 |
| language | English |
| last_indexed | 2024-03-12T05:32:33Z |
| publishDate | 2015-07-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Judgment and Decision Making |
| spelling | doaj.art-7a0e049bc8cc450dacf5faa8292194e52023-09-03T06:50:51ZengCambridge University PressJudgment and Decision Making1930-29752015-07-01104386399Willingness to test for BRCA1/2 in high risk women: Influenced by risk perception and family experience, rather than by objective or subjective numeracy?Talya Miron-ShatzYaniv HanochBenjamin A. KatzGlen M. DonigerElissa M. OzanneGenetic testing for breast and ovarian cancer can help target prevention programs, and possibly reduce morbidity and mortality. A positive result of BRCA1/2 is a substantial risk factor for breast and ovarian cancer, and its detection often leads to risk reduction interventions such as increased screening, prophylactic mastectomy and oophorectomy. We examined predictors of the decision to undergo cancer related genetic testing: perceived risk, family risk of breast or ovarian cancer, and numeracy as predictors of the decision to test among women at high risk of breast cancer. Stepwise regression analysis of survey responses from 459 women registered in the Cancer Genetics Network revealed greater likelihood to test for women with more family history, higher perceived risk of mutation, or Ashkenazi descent. Neither subjective nor objective numeracy was associated with the decision to test, although we replicated an earlier finding that subjective numeracy predicted willingness to pay for testing. Findings underscore the need for genetic counselling that disentangles risk perception from objective information to promote better decision-making in the context of genetic testing. Highlighting these factors is crucial for public health campaigns, as well as to clinic-based testing and direct-to-consumer testing.http://journal.sjdm.org/15/15201/jdm15201.pdfwillingness to test genetic testing breast cancer BRCA1 and 2 subjective numeracy family history. early detection.NAKeywords |
| spellingShingle | Talya Miron-Shatz Yaniv Hanoch Benjamin A. Katz Glen M. Doniger Elissa M. Ozanne Willingness to test for BRCA1/2 in high risk women: Influenced by risk perception and family experience, rather than by objective or subjective numeracy? Judgment and Decision Making willingness to test genetic testing breast cancer BRCA1 and 2 subjective numeracy family history. early detection.NAKeywords |
| title | Willingness to test
for BRCA1/2 in high risk women: Influenced by risk perception and family
experience, rather than by objective or subjective numeracy? |
| title_full | Willingness to test
for BRCA1/2 in high risk women: Influenced by risk perception and family
experience, rather than by objective or subjective numeracy? |
| title_fullStr | Willingness to test
for BRCA1/2 in high risk women: Influenced by risk perception and family
experience, rather than by objective or subjective numeracy? |
| title_full_unstemmed | Willingness to test
for BRCA1/2 in high risk women: Influenced by risk perception and family
experience, rather than by objective or subjective numeracy? |
| title_short | Willingness to test
for BRCA1/2 in high risk women: Influenced by risk perception and family
experience, rather than by objective or subjective numeracy? |
| title_sort | willingness to test for brca1 2 in high risk women influenced by risk perception and family experience rather than by objective or subjective numeracy |
| topic | willingness to test genetic testing breast cancer BRCA1 and 2 subjective numeracy family history. early detection.NAKeywords |
| url | http://journal.sjdm.org/15/15201/jdm15201.pdf |
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