Egyptian evidence-based consensus on clinical practice recommendations for the management of familial Mediterranean fever
Abstract Background We aimed to provide a consensus, evidence-based recommendations for the diagnosis, evaluation, and treat-to-target management of children living with FMF. This study was carried out to achieve an expert consensus on a treat-to-target management strategy for FMF using the Delphi t...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-06-01
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| Series: | Egyptian Rheumatology and Rehabilitation |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43166-022-00132-2 |
| _version_ | 1818547175097892864 |
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| author | S. Salah H. Lotfy M. H. Abu-Zaid M. El Gaafary H. Abdulhady H. Salah E. Abd El-Latif Y. Farag M. Eissa S. Esam Maher A. Radwan Amira T. El-Shanawany B. M. Medhat D. El Mikkawy D. M. Mosa G. El Deriny M. Mortada N. S. Osman N. A. Fouad N. E. Elkaraly S. S. Mohamed S. A. Tabra W. A. Hassan Y. Amer S. I. Nasef Y. El Miedany |
| author_facet | S. Salah H. Lotfy M. H. Abu-Zaid M. El Gaafary H. Abdulhady H. Salah E. Abd El-Latif Y. Farag M. Eissa S. Esam Maher A. Radwan Amira T. El-Shanawany B. M. Medhat D. El Mikkawy D. M. Mosa G. El Deriny M. Mortada N. S. Osman N. A. Fouad N. E. Elkaraly S. S. Mohamed S. A. Tabra W. A. Hassan Y. Amer S. I. Nasef Y. El Miedany |
| author_sort | S. Salah |
| collection | DOAJ |
| description | Abstract Background We aimed to provide a consensus, evidence-based recommendations for the diagnosis, evaluation, and treat-to-target management of children living with FMF. This study was carried out to achieve an expert consensus on a treat-to-target management strategy for FMF using the Delphi technique. The preliminary scientific committee identified a total of 17 key clinical questions according to the Patient/Population, Intervention, Comparison, and Outcomes (PICO) approach. An evidence-based, systematic, literature review was conducted to compile evidence for the benefits and harms associated with JIA treatments. The core leadership team identified researchers and clinicians with expertise in FMF management. Delphi process was implemented (2 rounds) to reach a consensus on the management recommendations of FMF patients. Results Twenty-one expert panel participated in the 2 rounds with a response rate of 100%. A total of 12 recommendations, categorized into 2 sections (4 in the diagnosis section and 8 in management), were obtained. The agreement with the recommendations (rank 7–9) ranged from 85.7 to 100%. The consensus was reached (i.e., ≥75% of respondents strongly agreed or agreed) on all the clinical standards. Algorithms for management have been also developed. Conclusion A wide and representative panel of experts established a consensus regarding the management of FMF. The developed guidelines provide a comprehensive treat-to-target approach to the management of FMF for all healthcare professionals who are involved in its management. |
| first_indexed | 2024-12-12T08:03:12Z |
| format | Article |
| id | doaj.art-7a0f7711237d407885e09ddadc7e5646 |
| institution | Directory Open Access Journal |
| issn | 1110-161X 2090-3235 |
| language | English |
| last_indexed | 2024-12-12T08:03:12Z |
| publishDate | 2022-06-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Egyptian Rheumatology and Rehabilitation |
| spelling | doaj.art-7a0f7711237d407885e09ddadc7e56462022-12-22T00:32:04ZengSpringerOpenEgyptian Rheumatology and Rehabilitation1110-161X2090-32352022-06-0149111510.1186/s43166-022-00132-2Egyptian evidence-based consensus on clinical practice recommendations for the management of familial Mediterranean feverS. Salah0H. Lotfy1M. H. Abu-Zaid2M. El Gaafary3H. Abdulhady4H. Salah5E. Abd El-Latif6Y. Farag7M. Eissa8S. Esam Maher9A. Radwan10Amira T. El-Shanawany11B. M. Medhat12D. El Mikkawy13D. M. Mosa14G. El Deriny15M. Mortada16N. S. Osman17N. A. Fouad18N. E. Elkaraly19S. S. Mohamed20S. A. Tabra21W. A. Hassan22Y. Amer23S. I. Nasef24Y. El Miedany25Cairo UniversityCairo UniversityRheumatology and Rehabilitation Department, Tanta UniversityAin Shams UniversityAin Shams UniversityCairo UniversityAlexandria UniversityCairo UniversityCairo UniversityMinia UniversitySohag UniversityMenoufia UniversityCairo UniversityAin Shams UniversityMansoura UniversityAlexandria UniversityZagazig UniversityAssiut UniversityFayoum UniversitySuez Canal UniversityCairo UniversityRheumatology and Rehabilitation Department, Tanta UniversityBenha UniversityZagazig UniversitySuez Canal UniversityAin Shams UniversityAbstract Background We aimed to provide a consensus, evidence-based recommendations for the diagnosis, evaluation, and treat-to-target management of children living with FMF. This study was carried out to achieve an expert consensus on a treat-to-target management strategy for FMF using the Delphi technique. The preliminary scientific committee identified a total of 17 key clinical questions according to the Patient/Population, Intervention, Comparison, and Outcomes (PICO) approach. An evidence-based, systematic, literature review was conducted to compile evidence for the benefits and harms associated with JIA treatments. The core leadership team identified researchers and clinicians with expertise in FMF management. Delphi process was implemented (2 rounds) to reach a consensus on the management recommendations of FMF patients. Results Twenty-one expert panel participated in the 2 rounds with a response rate of 100%. A total of 12 recommendations, categorized into 2 sections (4 in the diagnosis section and 8 in management), were obtained. The agreement with the recommendations (rank 7–9) ranged from 85.7 to 100%. The consensus was reached (i.e., ≥75% of respondents strongly agreed or agreed) on all the clinical standards. Algorithms for management have been also developed. Conclusion A wide and representative panel of experts established a consensus regarding the management of FMF. The developed guidelines provide a comprehensive treat-to-target approach to the management of FMF for all healthcare professionals who are involved in its management.https://doi.org/10.1186/s43166-022-00132-2Familial Mediterranean feverFMFColchicineEgyptian guidelines for FMF |
| spellingShingle | S. Salah H. Lotfy M. H. Abu-Zaid M. El Gaafary H. Abdulhady H. Salah E. Abd El-Latif Y. Farag M. Eissa S. Esam Maher A. Radwan Amira T. El-Shanawany B. M. Medhat D. El Mikkawy D. M. Mosa G. El Deriny M. Mortada N. S. Osman N. A. Fouad N. E. Elkaraly S. S. Mohamed S. A. Tabra W. A. Hassan Y. Amer S. I. Nasef Y. El Miedany Egyptian evidence-based consensus on clinical practice recommendations for the management of familial Mediterranean fever Egyptian Rheumatology and Rehabilitation Familial Mediterranean fever FMF Colchicine Egyptian guidelines for FMF |
| title | Egyptian evidence-based consensus on clinical practice recommendations for the management of familial Mediterranean fever |
| title_full | Egyptian evidence-based consensus on clinical practice recommendations for the management of familial Mediterranean fever |
| title_fullStr | Egyptian evidence-based consensus on clinical practice recommendations for the management of familial Mediterranean fever |
| title_full_unstemmed | Egyptian evidence-based consensus on clinical practice recommendations for the management of familial Mediterranean fever |
| title_short | Egyptian evidence-based consensus on clinical practice recommendations for the management of familial Mediterranean fever |
| title_sort | egyptian evidence based consensus on clinical practice recommendations for the management of familial mediterranean fever |
| topic | Familial Mediterranean fever FMF Colchicine Egyptian guidelines for FMF |
| url | https://doi.org/10.1186/s43166-022-00132-2 |
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