Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes
A phenome-wide association study and polygenic risk score analysis identifies several loci linked to metabolic disease and type 2 diabetes in the Taiwanese population.
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-11-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-04168-0 |
| _version_ | 1828156063667453952 |
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| author | Chia-Jung Lee Ting-Huei Chen Aylwin Ming Wee Lim Chien-Ching Chang Jia-Jyun Sie Pei-Lung Chen Su-Wei Chang Shang-Jung Wu Chia-Lin Hsu Ai-Ru Hsieh Wei-Shiung Yang Cathy S. J. Fann |
| author_facet | Chia-Jung Lee Ting-Huei Chen Aylwin Ming Wee Lim Chien-Ching Chang Jia-Jyun Sie Pei-Lung Chen Su-Wei Chang Shang-Jung Wu Chia-Lin Hsu Ai-Ru Hsieh Wei-Shiung Yang Cathy S. J. Fann |
| author_sort | Chia-Jung Lee |
| collection | DOAJ |
| description | A phenome-wide association study and polygenic risk score analysis identifies several loci linked to metabolic disease and type 2 diabetes in the Taiwanese population. |
| first_indexed | 2024-04-11T23:03:51Z |
| format | Article |
| id | doaj.art-7a0fb0c879f44806bc21cfd22dfb3009 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-11T23:03:51Z |
| publishDate | 2022-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-7a0fb0c879f44806bc21cfd22dfb30092022-12-22T03:58:04ZengNature PortfolioCommunications Biology2399-36422022-11-01511910.1038/s42003-022-04168-0Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetesChia-Jung Lee0Ting-Huei Chen1Aylwin Ming Wee Lim2Chien-Ching Chang3Jia-Jyun Sie4Pei-Lung Chen5Su-Wei Chang6Shang-Jung Wu7Chia-Lin Hsu8Ai-Ru Hsieh9Wei-Shiung Yang10Cathy S. J. Fann11Institute of Biomedical Sciences, Academia SinicaDepartment of Mathematics and Statistics, Laval UniversityInstitute of Biomedical Sciences, Academia SinicaInstitute of Biomedical Sciences, Academia SinicaDepartment of Mathematics, National Changhua University of EducationGraduate Institute of Medical Genomics and Proteomics, College of Medicine, National Taiwan UniversityClinical Informatics and Medical Statistics Research Center, Chang Gung UniversityInstitute of Biomedical Sciences, Academia SinicaInstitute of Biomedical Sciences, Academia SinicaDepartment of Statistics, Tamkang UniversityGraduate Institute of Medical Genomics and Proteomics, College of Medicine, National Taiwan UniversityInstitute of Biomedical Sciences, Academia SinicaA phenome-wide association study and polygenic risk score analysis identifies several loci linked to metabolic disease and type 2 diabetes in the Taiwanese population.https://doi.org/10.1038/s42003-022-04168-0 |
| spellingShingle | Chia-Jung Lee Ting-Huei Chen Aylwin Ming Wee Lim Chien-Ching Chang Jia-Jyun Sie Pei-Lung Chen Su-Wei Chang Shang-Jung Wu Chia-Lin Hsu Ai-Ru Hsieh Wei-Shiung Yang Cathy S. J. Fann Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes Communications Biology |
| title | Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes |
| title_full | Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes |
| title_fullStr | Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes |
| title_full_unstemmed | Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes |
| title_short | Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes |
| title_sort | phenome wide analysis of taiwan biobank reveals novel glycemia related loci and genetic risks for diabetes |
| url | https://doi.org/10.1038/s42003-022-04168-0 |
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