Membrane platform protein PulF of the Klebsiella type II secretion system forms a trimeric ion channel essential for endopilus assembly and protein secretion

Membrane platform protein PulF of the Klebsiella type II secretion system forms a trimeric ion channel essential for endopilus assembly and protein secretion

ABSTRACTType IV pili and type II secretion systems (T2SS) are crucial for bacterial adaptation, virulence, and environmental impact. A common mechanism underlying their multiple functions involves assembly of dynamic plasma membrane-anchored filaments—the (endo)pili. The cytoplasmic ATPase motor Gsp...

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Bibliografiska uppgifter
Huvudupphovsmän: Ingrid Guilvout, Firdaus Samsudin, Roland G. Huber, Peter J. Bond, Benjamin Bardiaux, Olivera Francetic
Materialtyp: Artikel
Språk:English
Publicerad: American Society for Microbiology 2024-01-01
Serie:mBio
Ämnen:
type II secretion system
type IV pili
type IV filaments
ion channel
cardiolipin
residue coevolution
Länkar:https://journals.asm.org/doi/10.1128/mbio.01423-23

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