Effect of mucosal adjuvant IL-1β on heterotypic immunity in a pig influenza model

Effect of mucosal adjuvant IL-1β on heterotypic immunity in a pig influenza model

T cell responses directed against highly conserved viral proteins contribute to the clearance of the influenza virus and confer broadly cross-reactive and protective immune responses against a range of influenza viruses in mice and ferrets. We examined the protective efficacy of mucosal delivery of...

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Main Authors: Anna Schmidt, Basudev Paudyal, Sonia Villanueva-Hernández, Adam Mcnee, Eleni Vatzia, Brigid Veronica Carr, Selma Schmidt, Amy Mccarron, Veronica Martini, Silke Schroedel, Christian Thirion, Ryan Waters, Francisco J. Salguero, Wilhelm Gerner, Matthias Tenbusch, Elma Tchilian
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
influenza virus
pig
mucosal immunity
IL-1β
heterotypic protection
porcine B cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1181716/full

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