Bioaffinity Nanoprobes for Foodborne Pathogen Sensing
Bioaffinity nanoprobes are a type of biosensor that utilize the specific binding properties of biological molecules, such as antibodies, enzymes, and nucleic acids, for the detection of foodborne pathogens. These probes serve as nanosensors and can provide highly specific and sensitive detection of...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Micromachines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-666X/14/6/1122 |
| _version_ | 1827736408604803072 |
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| author | Tracy Ann Bruce-Tagoe Michael K. Danquah |
| author_facet | Tracy Ann Bruce-Tagoe Michael K. Danquah |
| author_sort | Tracy Ann Bruce-Tagoe |
| collection | DOAJ |
| description | Bioaffinity nanoprobes are a type of biosensor that utilize the specific binding properties of biological molecules, such as antibodies, enzymes, and nucleic acids, for the detection of foodborne pathogens. These probes serve as nanosensors and can provide highly specific and sensitive detection of pathogens in food samples, making them an attractive option for food safety testing. The advantages of bioaffinity nanoprobes include their ability to detect low levels of pathogens, rapid analysis time, and cost-effectiveness. However, limitations include the need for specialized equipment and the potential for cross-reactivity with other biological molecules. Current research efforts focus on optimizing the performance of bioaffinity probes and expanding their application in the food industry. This article discusses relevant analytical methods, such as surface plasmon resonance (SPR) analysis, Fluorescence Resonance Energy Transfer (FRET) measurements, circular dichroism, and flow cytometry, that are used to evaluate the efficacy of bioaffinity nanoprobes. Additionally, it discusses advances in the development and application of biosensors in monitoring foodborne pathogens. |
| first_indexed | 2024-03-11T02:09:19Z |
| format | Article |
| id | doaj.art-7a12deea5b10449caa95845e146a1180 |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-03-11T02:09:19Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-7a12deea5b10449caa95845e146a11802023-11-18T11:38:45ZengMDPI AGMicromachines2072-666X2023-05-01146112210.3390/mi14061122Bioaffinity Nanoprobes for Foodborne Pathogen SensingTracy Ann Bruce-Tagoe0Michael K. Danquah1Department of Chemical Engineering, University of Tennessee, Chattanooga 615 McCallie Ave, Chattanooga, TN 37403, USADepartment of Chemical Engineering, University of Tennessee, Chattanooga 615 McCallie Ave, Chattanooga, TN 37403, USABioaffinity nanoprobes are a type of biosensor that utilize the specific binding properties of biological molecules, such as antibodies, enzymes, and nucleic acids, for the detection of foodborne pathogens. These probes serve as nanosensors and can provide highly specific and sensitive detection of pathogens in food samples, making them an attractive option for food safety testing. The advantages of bioaffinity nanoprobes include their ability to detect low levels of pathogens, rapid analysis time, and cost-effectiveness. However, limitations include the need for specialized equipment and the potential for cross-reactivity with other biological molecules. Current research efforts focus on optimizing the performance of bioaffinity probes and expanding their application in the food industry. This article discusses relevant analytical methods, such as surface plasmon resonance (SPR) analysis, Fluorescence Resonance Energy Transfer (FRET) measurements, circular dichroism, and flow cytometry, that are used to evaluate the efficacy of bioaffinity nanoprobes. Additionally, it discusses advances in the development and application of biosensors in monitoring foodborne pathogens.https://www.mdpi.com/2072-666X/14/6/1122aptamernanoprobebiosensorbioaffinityfood safety |
| spellingShingle | Tracy Ann Bruce-Tagoe Michael K. Danquah Bioaffinity Nanoprobes for Foodborne Pathogen Sensing Micromachines aptamer nanoprobe biosensor bioaffinity food safety |
| title | Bioaffinity Nanoprobes for Foodborne Pathogen Sensing |
| title_full | Bioaffinity Nanoprobes for Foodborne Pathogen Sensing |
| title_fullStr | Bioaffinity Nanoprobes for Foodborne Pathogen Sensing |
| title_full_unstemmed | Bioaffinity Nanoprobes for Foodborne Pathogen Sensing |
| title_short | Bioaffinity Nanoprobes for Foodborne Pathogen Sensing |
| title_sort | bioaffinity nanoprobes for foodborne pathogen sensing |
| topic | aptamer nanoprobe biosensor bioaffinity food safety |
| url | https://www.mdpi.com/2072-666X/14/6/1122 |
| work_keys_str_mv | AT tracyannbrucetagoe bioaffinitynanoprobesforfoodbornepathogensensing AT michaelkdanquah bioaffinitynanoprobesforfoodbornepathogensensing |