Estimating human health risks associated with heavy metal exposure from bottled water using Monte Carlo simulation

Water is the most important non-organic compound for living cells, and the life of all living organisms depends on it. Water is not found purely in nature, but it always contains some solutes, suspended matters and soluble gases. In this study, 11 bottled water brands (500 mL) were sampled across th...

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Main Authors: Nezam Mirzaei, Safa Kalteh, Hakime Zamani-Badi, Heshmatallah Moradpour, Zeinab Parmoozeh, Mansour Baziar
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023078556
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author Nezam Mirzaei
Safa Kalteh
Hakime Zamani-Badi
Heshmatallah Moradpour
Zeinab Parmoozeh
Mansour Baziar
author_facet Nezam Mirzaei
Safa Kalteh
Hakime Zamani-Badi
Heshmatallah Moradpour
Zeinab Parmoozeh
Mansour Baziar
author_sort Nezam Mirzaei
collection DOAJ
description Water is the most important non-organic compound for living cells, and the life of all living organisms depends on it. Water is not found purely in nature, but it always contains some solutes, suspended matters and soluble gases. In this study, 11 bottled water brands (500 mL) were sampled across the Kashan city market to determine the concentration of selected heavy metals (Cr, Cd, Pb, Ni and As) and evaluated their potential risks following consumption. The concentration range of Cr, Cd, Pb, Ni and As were 5–34 μg/L, 1.5–7 μg/L, 1–7 μg/L, 2–29 μg/L, <LOD – 3.5 μg/L, respectively. The heavy metals (HMs) concentration in this study was compared with other national and international studies on bottled water and other drinking water sources. Additionally, the results of non-carcinogenic health risk assessments using point estimations and Monte Carlo Simulations (MCS) showed that the concentration of HMs in none of the samples pose adverse health effects. However, it was found that drinking the studied bottled water may potentially lead to carcinogenicity over the lifetime. Lack of including spring water and larger-sized (1.5 L) bottled water samples, though less consumed than the samples of this study and lack of study on children's exposure level can be mentioned as potential limitations.
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spelling doaj.art-7a138e3fd6ec4d3f9172bd619ac2b3f12023-10-30T06:06:53ZengElsevierHeliyon2405-84402023-10-01910e20647Estimating human health risks associated with heavy metal exposure from bottled water using Monte Carlo simulationNezam Mirzaei0Safa Kalteh1Hakime Zamani-Badi2Heshmatallah Moradpour3Zeinab Parmoozeh4Mansour Baziar5Department of Environmental Health Engineering, Social Determinants of Health (SDH) Research Center, Kashan University of Medical Sciences, Kashan, IranDepartment of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Health, Safety and Environment Management, Faculty of Health, Kashan University of Medical Sciences, Kashan, IranDepartment of Environmental Health Engineering, Social Determinants of Health (SDH) Research Center, Kashan University of Medical Sciences, Kashan, IranDepartment of Environmental Health Engineering, Social Determinants of Health (SDH) Research Center, Kashan University of Medical Sciences, Kashan, IranDepartment of Environmental Health Engineering, Ferdows Faculty of Medical Sciences, Birjand University of Medical Sciences, Birjand, Iran; Corresponding author.Water is the most important non-organic compound for living cells, and the life of all living organisms depends on it. Water is not found purely in nature, but it always contains some solutes, suspended matters and soluble gases. In this study, 11 bottled water brands (500 mL) were sampled across the Kashan city market to determine the concentration of selected heavy metals (Cr, Cd, Pb, Ni and As) and evaluated their potential risks following consumption. The concentration range of Cr, Cd, Pb, Ni and As were 5–34 μg/L, 1.5–7 μg/L, 1–7 μg/L, 2–29 μg/L, <LOD – 3.5 μg/L, respectively. The heavy metals (HMs) concentration in this study was compared with other national and international studies on bottled water and other drinking water sources. Additionally, the results of non-carcinogenic health risk assessments using point estimations and Monte Carlo Simulations (MCS) showed that the concentration of HMs in none of the samples pose adverse health effects. However, it was found that drinking the studied bottled water may potentially lead to carcinogenicity over the lifetime. Lack of including spring water and larger-sized (1.5 L) bottled water samples, though less consumed than the samples of this study and lack of study on children's exposure level can be mentioned as potential limitations.http://www.sciencedirect.com/science/article/pii/S2405844023078556Bottled waterHeavy metalsHuman risk assessmentKashan
spellingShingle Nezam Mirzaei
Safa Kalteh
Hakime Zamani-Badi
Heshmatallah Moradpour
Zeinab Parmoozeh
Mansour Baziar
Estimating human health risks associated with heavy metal exposure from bottled water using Monte Carlo simulation
Heliyon
Bottled water
Heavy metals
Human risk assessment
Kashan
title Estimating human health risks associated with heavy metal exposure from bottled water using Monte Carlo simulation
title_full Estimating human health risks associated with heavy metal exposure from bottled water using Monte Carlo simulation
title_fullStr Estimating human health risks associated with heavy metal exposure from bottled water using Monte Carlo simulation
title_full_unstemmed Estimating human health risks associated with heavy metal exposure from bottled water using Monte Carlo simulation
title_short Estimating human health risks associated with heavy metal exposure from bottled water using Monte Carlo simulation
title_sort estimating human health risks associated with heavy metal exposure from bottled water using monte carlo simulation
topic Bottled water
Heavy metals
Human risk assessment
Kashan
url http://www.sciencedirect.com/science/article/pii/S2405844023078556
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AT hakimezamanibadi estimatinghumanhealthrisksassociatedwithheavymetalexposurefrombottledwaterusingmontecarlosimulation
AT heshmatallahmoradpour estimatinghumanhealthrisksassociatedwithheavymetalexposurefrombottledwaterusingmontecarlosimulation
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