A Novel Fibromodulin Antagonist Peptide RP4 Exerts Antitumor Effects on Colorectal Cancer

A Novel Fibromodulin Antagonist Peptide RP4 Exerts Antitumor Effects on Colorectal Cancer

Colorectal cancer (CRC) is the leading cause of cancer-related deaths worldwide. Fibromodulin (FMOD) is the main proteoglycan that contributes to extracellular matrix (ECM) remodeling by binding to matrix molecules, thereby playing an essential role in tumor growth and metastasis. There are still no...

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Bibliographic Details
Main Authors:	Ting Deng, Yibo Hou, Gaoyang Lin, Chunyan Feng, Kewei Liu, Wenke Chen, Wei Wei, Laiqiang Huang, Xiaoyong Dai
Format:	Article
Language:	English
Published:	MDPI AG 2023-03-01
Series:	Pharmaceutics
Subjects:	fibromodulin colorectal cancer metastasis tumor microenvironment AKT signaling pathway Wnt/β-catenin signaling pathway
Online Access:	https://www.mdpi.com/1999-4923/15/3/944

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