“Exercise induced asthma” is not always asthma
A 25 year old woman was referred to our center for further evaluation of an exercise-induced dyspnea. Moreover, the patient suffered from hoarseness and recurrent sinusitis and otitis.After initially finding nothing suspicious, a spiro-ergometry was performed. Interestingly, we saw a relevant limita...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-01-01
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| Series: | Respiratory Medicine Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007117303775 |
| _version_ | 1818309966954496000 |
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| author | Thomas Kofler Thomas Daikeler Spasenija Savic Prince Yvonne Holzmann Jens Bremerich Michael Tamm Kathleen Jahn |
| author_facet | Thomas Kofler Thomas Daikeler Spasenija Savic Prince Yvonne Holzmann Jens Bremerich Michael Tamm Kathleen Jahn |
| author_sort | Thomas Kofler |
| collection | DOAJ |
| description | A 25 year old woman was referred to our center for further evaluation of an exercise-induced dyspnea. Moreover, the patient suffered from hoarseness and recurrent sinusitis and otitis.After initially finding nothing suspicious, a spiro-ergometry was performed. Interestingly, we saw a relevant limitation of the inspiratory flow-volume curve under maximal exercise load. Further evaluation (in particular the bronchoscopy and the resulting biopsies) led us to the final diagnosis of a granulomatosis with polyangiitis.After 4 weeks of an established therapy regime with prednisone and rituximab the prior detected subglottic stenosis and the inspiratory flow-volume curve limitation could no longer detected.We describe a rare differential diagnosis of an exercise-induced asthma and we underline the importance of a multimodal therapy concept. We highlight the critical nature of the flow-volume curve in spiro-ergometry under maximal exercise load. We recommend frequent follow-up control visits to monitor the subglottic stenosis. Keywords: Asthma, Exercise induced, GPA |
| first_indexed | 2024-12-13T07:38:34Z |
| format | Article |
| id | doaj.art-7a16dcc956474b08aab2d52d025574c7 |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-12-13T07:38:34Z |
| publishDate | 2018-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-7a16dcc956474b08aab2d52d025574c72022-12-21T23:55:01ZengElsevierRespiratory Medicine Case Reports2213-00712018-01-0124138142“Exercise induced asthma” is not always asthmaThomas Kofler0Thomas Daikeler1Spasenija Savic Prince2Yvonne Holzmann3Jens Bremerich4Michael Tamm5Kathleen Jahn6Department of Pneumology, University Hospital Basel, Switzerland; Corresponding author.Rheumatology Division, University Hospital Basel, Basel, SwitzerlandInstitute of Pathology, University Hospital Basel, SwitzerlandDepartment of Nephrology and Transplantational Medicine, University Hospital Basel, SwitzerlandDepartment of Cardiothorac Radiology, University Hospital Basel, SwitzerlandDepartment of Pneumology, University Hospital Basel, SwitzerlandDepartment of Pneumology, University Hospital Basel, SwitzerlandA 25 year old woman was referred to our center for further evaluation of an exercise-induced dyspnea. Moreover, the patient suffered from hoarseness and recurrent sinusitis and otitis.After initially finding nothing suspicious, a spiro-ergometry was performed. Interestingly, we saw a relevant limitation of the inspiratory flow-volume curve under maximal exercise load. Further evaluation (in particular the bronchoscopy and the resulting biopsies) led us to the final diagnosis of a granulomatosis with polyangiitis.After 4 weeks of an established therapy regime with prednisone and rituximab the prior detected subglottic stenosis and the inspiratory flow-volume curve limitation could no longer detected.We describe a rare differential diagnosis of an exercise-induced asthma and we underline the importance of a multimodal therapy concept. We highlight the critical nature of the flow-volume curve in spiro-ergometry under maximal exercise load. We recommend frequent follow-up control visits to monitor the subglottic stenosis. Keywords: Asthma, Exercise induced, GPAhttp://www.sciencedirect.com/science/article/pii/S2213007117303775 |
| spellingShingle | Thomas Kofler Thomas Daikeler Spasenija Savic Prince Yvonne Holzmann Jens Bremerich Michael Tamm Kathleen Jahn “Exercise induced asthma” is not always asthma Respiratory Medicine Case Reports |
| title | “Exercise induced asthma” is not always asthma |
| title_full | “Exercise induced asthma” is not always asthma |
| title_fullStr | “Exercise induced asthma” is not always asthma |
| title_full_unstemmed | “Exercise induced asthma” is not always asthma |
| title_short | “Exercise induced asthma” is not always asthma |
| title_sort | exercise induced asthma is not always asthma |
| url | http://www.sciencedirect.com/science/article/pii/S2213007117303775 |
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