The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group
Abstract Cognitive, behavioural, and functional assessment is crucial in longitudinal studies of neurodegenerative dementias (NDD). Central issues, such as the definition of the study population (asymptomatic, at risk, or individuals with dementia), the detection of change/decline, and the assessmen...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-04-01
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| Series: | Alzheimer’s Research & Therapy |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13195-017-0254-x |
| _version_ | 1819120085902557184 |
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| author | Alberto Costa Thomas Bak Paolo Caffarra Carlo Caltagirone Mathieu Ceccaldi Fabienne Collette Sebastian Crutch Sergio Della Sala Jean François Démonet Bruno Dubois Emrah Duzel Peter Nestor Sokratis G. Papageorgiou Eric Salmon Sietske Sikkes Pietro Tiraboschi Wiesje M. van der Flier Pieter Jelle Visser Stefano F. Cappa |
| author_facet | Alberto Costa Thomas Bak Paolo Caffarra Carlo Caltagirone Mathieu Ceccaldi Fabienne Collette Sebastian Crutch Sergio Della Sala Jean François Démonet Bruno Dubois Emrah Duzel Peter Nestor Sokratis G. Papageorgiou Eric Salmon Sietske Sikkes Pietro Tiraboschi Wiesje M. van der Flier Pieter Jelle Visser Stefano F. Cappa |
| author_sort | Alberto Costa |
| collection | DOAJ |
| description | Abstract Cognitive, behavioural, and functional assessment is crucial in longitudinal studies of neurodegenerative dementias (NDD). Central issues, such as the definition of the study population (asymptomatic, at risk, or individuals with dementia), the detection of change/decline, and the assessment of relevant outcomes depend on quantitative measures of cognitive, behavioural, and functional status. Currently, we are far from having available reliable protocols and tools for the assessment of dementias in Europe. The main problems are the heterogeneity of the tools used across different European countries, the lack of standardisation of administration and scoring methods across centres, and the limited information available about the psychometric properties of many tests currently in widespread use. This situation makes it hard to compare results across studies carried out in different centres, thus hampering research progress, in particular towards the contribution to a “big data” common data set. We present here the results of a project funded by the Joint Program for Neurodegenerative Diseases (JPND) and by the Italian Ministry of Health. The project aimed at providing a consensus framework for the harmonisation of assessment tools to be applied to research in neurodegenerative disorders affecting cognition across Europe. A panel of European experts reviewed the current methods of neuropsychological assessment, identified pending issues, and made recommendations for the harmonisation of neuropsychological assessment of neurodegenerative dementias in Europe. A consensus was achieved on the general recommendations to be followed in developing procedures and tools for neuropsychological assessment, with the aim of harmonising tools and procedures to achieve more reliable data on the cognitive-behavioural examination. The results of this study should be considered as a first step to enhancing a common view and practise on NDD assessment across European countries. |
| first_indexed | 2024-12-22T06:15:04Z |
| format | Article |
| id | doaj.art-7a174b06e477406b9c91963bd8fb89ac |
| institution | Directory Open Access Journal |
| issn | 1758-9193 |
| language | English |
| last_indexed | 2024-12-22T06:15:04Z |
| publishDate | 2017-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Alzheimer’s Research & Therapy |
| spelling | doaj.art-7a174b06e477406b9c91963bd8fb89ac2022-12-21T18:36:07ZengBMCAlzheimer’s Research & Therapy1758-91932017-04-019111510.1186/s13195-017-0254-xThe need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working GroupAlberto Costa0Thomas Bak1Paolo Caffarra2Carlo Caltagirone3Mathieu Ceccaldi4Fabienne Collette5Sebastian Crutch6Sergio Della Sala7Jean François Démonet8Bruno Dubois9Emrah Duzel10Peter Nestor11Sokratis G. Papageorgiou12Eric Salmon13Sietske Sikkes14Pietro Tiraboschi15Wiesje M. van der Flier16Pieter Jelle Visser17Stefano F. Cappa18Niccolò Cusano UniversityUniversity of EdinburghUniversity of ParmaIRCCS Fondazione Santa LuciaUniversity Hospital La TimoneNational Fund for Scientific Research (F.R.S-FNRS)Dementia Research Centre, UCL Institute of Neurology, University College of LondonIRCCS Fondazione Santa LuciaLeenaards Memory Centre CHUV, Lausanne University HospitalInstitut de la Mémoire et de la Maladie d’Alzheimer (IMMA), Hôpital de la Pitié-SalpêtrièreDementia Research Centre, UCL Institute of Neurology, University College of LondonGerman Center for Neurodegenerative Diseases (DZNE)Medical School, National and Kapodistrian University of AthensCyclotron Research Centre, University of LiegeAlzheimer Center/dpt Neurology, VU University Medical Center of Amsterdam, Amsterdam NeuroscienceFondazione IRCCS Istituto Neurologico Carlo BestaAlzheimer Center/dpt Neurology, VU University Medical Center of Amsterdam, Amsterdam NeuroscienceMaastricht University Medical CentreIUSS PaviaAbstract Cognitive, behavioural, and functional assessment is crucial in longitudinal studies of neurodegenerative dementias (NDD). Central issues, such as the definition of the study population (asymptomatic, at risk, or individuals with dementia), the detection of change/decline, and the assessment of relevant outcomes depend on quantitative measures of cognitive, behavioural, and functional status. Currently, we are far from having available reliable protocols and tools for the assessment of dementias in Europe. The main problems are the heterogeneity of the tools used across different European countries, the lack of standardisation of administration and scoring methods across centres, and the limited information available about the psychometric properties of many tests currently in widespread use. This situation makes it hard to compare results across studies carried out in different centres, thus hampering research progress, in particular towards the contribution to a “big data” common data set. We present here the results of a project funded by the Joint Program for Neurodegenerative Diseases (JPND) and by the Italian Ministry of Health. The project aimed at providing a consensus framework for the harmonisation of assessment tools to be applied to research in neurodegenerative disorders affecting cognition across Europe. A panel of European experts reviewed the current methods of neuropsychological assessment, identified pending issues, and made recommendations for the harmonisation of neuropsychological assessment of neurodegenerative dementias in Europe. A consensus was achieved on the general recommendations to be followed in developing procedures and tools for neuropsychological assessment, with the aim of harmonising tools and procedures to achieve more reliable data on the cognitive-behavioural examination. The results of this study should be considered as a first step to enhancing a common view and practise on NDD assessment across European countries.http://link.springer.com/article/10.1186/s13195-017-0254-xNeurodegenerative dementiaCognitive assessmentBehavioural assessmentNeuropsychological testsLongitudinal studiesEuropean research |
| spellingShingle | Alberto Costa Thomas Bak Paolo Caffarra Carlo Caltagirone Mathieu Ceccaldi Fabienne Collette Sebastian Crutch Sergio Della Sala Jean François Démonet Bruno Dubois Emrah Duzel Peter Nestor Sokratis G. Papageorgiou Eric Salmon Sietske Sikkes Pietro Tiraboschi Wiesje M. van der Flier Pieter Jelle Visser Stefano F. Cappa The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group Alzheimer’s Research & Therapy Neurodegenerative dementia Cognitive assessment Behavioural assessment Neuropsychological tests Longitudinal studies European research |
| title | The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group |
| title_full | The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group |
| title_fullStr | The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group |
| title_full_unstemmed | The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group |
| title_short | The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group |
| title_sort | need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in europe consensus document of the joint program for neurodegenerative diseases working group |
| topic | Neurodegenerative dementia Cognitive assessment Behavioural assessment Neuropsychological tests Longitudinal studies European research |
| url | http://link.springer.com/article/10.1186/s13195-017-0254-x |
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