The chronic effect of Kombucha Tea consumption on weight loss in diabetic rats

Background: Diabetes mellitus (DM) is a chronic disease with a relatively high prevalence in many populations throughout the world. Despite the availability of many synthetic drugs many diabetic patients are seeking herbal medications to relieve the symptoms of the disease. Kombucha tea is a ferment...

Full description

Bibliographic Details
Main Authors: Morshedi A, MH Dashti, A Rafati, MH Mosaddegh, AS Salami
Format: Article
Language:English
Published: Institue of Medicinal Plants, ACECR 2006-03-01
Series:Journal of Medicinal Plants
Subjects:
Online Access:http://jmp.ir/article-1-597-en.html
_version_ 1819107315807158272
author Morshedi A
MH Dashti
A Rafati
MH Mosaddegh
AS Salami
author_facet Morshedi A
MH Dashti
A Rafati
MH Mosaddegh
AS Salami
author_sort Morshedi A
collection DOAJ
description Background: Diabetes mellitus (DM) is a chronic disease with a relatively high prevalence in many populations throughout the world. Despite the availability of many synthetic drugs many diabetic patients are seeking herbal medications to relieve the symptoms of the disease. Kombucha tea is a fermented remedy which is produced by cultivation of Kombucha mushroom in sweet black tea solution and is consumed by many diabetic patients, but its efficacy and safety has not been scientifically evaluated.   Materials and Methods: This study was conducted to assess the chronic effect of Kombucha Tea consumption on weight loss in diabetic Rats. 42 male diabetic Wistar rats were divided into six groups. DM was induced by streptozotocin (60 mg/kg). Animals in 1st group (control) had free access to tap water the 2nd group (sham) consumed sweet black tea solution and the remaining 4 groups (test) received different dilutionts of Kombucha tea (25%, 50%, 75% and 100%) for 15 days instead of tap water. Animals in all groups were weighted before DM induction and in days 1, 3, 7 and 15 post DM inductions. The data were analyzed as Mean ± SEM of weights in different days and in different groups by using T-test and one way ANOVA.   Results: Our results showed that all groups had a significant weight loss due to DM induction (p< 0.05) which continued progressively in control group but in the sham and test groups there was a progressive weight gain during the 15 days of remedy consumption, so there was no significant difference between the weight of animals at the end of experiment and their weight before DM induction (p > 0.05). There was also not significant difference between the animal’s weight in sham and test groups at the end of this period (p > 0.05). Conclusion: In conclusion our findings indicate that both black tea and Kombucha tea prevent weight loss in diabetic rats which may be due to some active agents in black tea itself.
first_indexed 2024-12-22T02:52:05Z
format Article
id doaj.art-7a194114adef4981a86a9ddd4272b613
institution Directory Open Access Journal
issn 2717-204X
2717-2058
language English
last_indexed 2024-12-22T02:52:05Z
publishDate 2006-03-01
publisher Institue of Medicinal Plants, ACECR
record_format Article
series Journal of Medicinal Plants
spelling doaj.art-7a194114adef4981a86a9ddd4272b6132022-12-21T18:41:21ZengInstitue of Medicinal Plants, ACECRJournal of Medicinal Plants2717-204X2717-20582006-03-015171722The chronic effect of Kombucha Tea consumption on weight loss in diabetic ratsMorshedi A0MH Dashti1A Rafati2MH Mosaddegh3AS Salami4 1- Department of Physiology, Shahid Sadughi Medical University, Yazd 1- Department of Physiology, Shahid Sadughi Medical University, Yazd 1- Department of Physiology, Shahid Sadughi Medical University, Yazd 2- Department of Pharmacology, Shahid Sadughi Medical University, Yazd 1- Department of Physiology, Shahid Sadughi Medical University, Yazd Background: Diabetes mellitus (DM) is a chronic disease with a relatively high prevalence in many populations throughout the world. Despite the availability of many synthetic drugs many diabetic patients are seeking herbal medications to relieve the symptoms of the disease. Kombucha tea is a fermented remedy which is produced by cultivation of Kombucha mushroom in sweet black tea solution and is consumed by many diabetic patients, but its efficacy and safety has not been scientifically evaluated.   Materials and Methods: This study was conducted to assess the chronic effect of Kombucha Tea consumption on weight loss in diabetic Rats. 42 male diabetic Wistar rats were divided into six groups. DM was induced by streptozotocin (60 mg/kg). Animals in 1st group (control) had free access to tap water the 2nd group (sham) consumed sweet black tea solution and the remaining 4 groups (test) received different dilutionts of Kombucha tea (25%, 50%, 75% and 100%) for 15 days instead of tap water. Animals in all groups were weighted before DM induction and in days 1, 3, 7 and 15 post DM inductions. The data were analyzed as Mean ± SEM of weights in different days and in different groups by using T-test and one way ANOVA.   Results: Our results showed that all groups had a significant weight loss due to DM induction (p< 0.05) which continued progressively in control group but in the sham and test groups there was a progressive weight gain during the 15 days of remedy consumption, so there was no significant difference between the weight of animals at the end of experiment and their weight before DM induction (p > 0.05). There was also not significant difference between the animal’s weight in sham and test groups at the end of this period (p > 0.05). Conclusion: In conclusion our findings indicate that both black tea and Kombucha tea prevent weight loss in diabetic rats which may be due to some active agents in black tea itself.http://jmp.ir/article-1-597-en.htmlkombucha teablack teadiabetes mellitusweight lossrat
spellingShingle Morshedi A
MH Dashti
A Rafati
MH Mosaddegh
AS Salami
The chronic effect of Kombucha Tea consumption on weight loss in diabetic rats
Journal of Medicinal Plants
kombucha tea
black tea
diabetes mellitus
weight loss
rat
title The chronic effect of Kombucha Tea consumption on weight loss in diabetic rats
title_full The chronic effect of Kombucha Tea consumption on weight loss in diabetic rats
title_fullStr The chronic effect of Kombucha Tea consumption on weight loss in diabetic rats
title_full_unstemmed The chronic effect of Kombucha Tea consumption on weight loss in diabetic rats
title_short The chronic effect of Kombucha Tea consumption on weight loss in diabetic rats
title_sort chronic effect of kombucha tea consumption on weight loss in diabetic rats
topic kombucha tea
black tea
diabetes mellitus
weight loss
rat
url http://jmp.ir/article-1-597-en.html
work_keys_str_mv AT morshedia thechroniceffectofkombuchateaconsumptiononweightlossindiabeticrats
AT mhdashti thechroniceffectofkombuchateaconsumptiononweightlossindiabeticrats
AT arafati thechroniceffectofkombuchateaconsumptiononweightlossindiabeticrats
AT mhmosaddegh thechroniceffectofkombuchateaconsumptiononweightlossindiabeticrats
AT assalami thechroniceffectofkombuchateaconsumptiononweightlossindiabeticrats
AT morshedia chroniceffectofkombuchateaconsumptiononweightlossindiabeticrats
AT mhdashti chroniceffectofkombuchateaconsumptiononweightlossindiabeticrats
AT arafati chroniceffectofkombuchateaconsumptiononweightlossindiabeticrats
AT mhmosaddegh chroniceffectofkombuchateaconsumptiononweightlossindiabeticrats
AT assalami chroniceffectofkombuchateaconsumptiononweightlossindiabeticrats