Outcomes and Economic Evaluation in Delayed Two-Stage Breast Reconstruction in Romania: The Influence of Radiotherapy
The current paper is a retrospective cohort study conducted on sixty-seven patients who underwent two-stage breast reconstruction over a 5-year period (2015–2020). Forty-one (61.2%) patients received radiotherapy (RT group), and twenty-six (38.8%) did not (non-RT group). Data regarding patients, onc...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Current Oncology |
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| Online Access: | https://www.mdpi.com/1718-7729/30/2/149 |
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| author | Andrei Ludovic Porosnicu Stefania Mihaela Riza Ioana Antonia Stanculescu Sorin Viorel Parasca Cristian Radu Jecan Ruxandra Diana Sinescu |
| author_facet | Andrei Ludovic Porosnicu Stefania Mihaela Riza Ioana Antonia Stanculescu Sorin Viorel Parasca Cristian Radu Jecan Ruxandra Diana Sinescu |
| author_sort | Andrei Ludovic Porosnicu |
| collection | DOAJ |
| description | The current paper is a retrospective cohort study conducted on sixty-seven patients who underwent two-stage breast reconstruction over a 5-year period (2015–2020). Forty-one (61.2%) patients received radiotherapy (RT group), and twenty-six (38.8%) did not (non-RT group). Data regarding patients, oncological therapies, type of reconstruction, time of hospitalization, complications, and costs were collected. The statistical analysis was performed using IBM SPSS Statistics 25. General complications were noted for 18 patients (43.9%) in the RT group and for 7 patients (26.9%) in the non-RT group. Major complications were observed only in the first group (five patients–12.2%). The mean time of hospitalization in the RT group was 14.83 days for patients with complications versus 9.83 days for those without complications and 15.5 days versus 8.63 days, respectively, in the non-RT group. The mean cost for patients without complications was 235.64 euros, whereas the cost for patients with complications was 330.24 euros (<i>p</i> = 0.001). Radiation therapy can affect the overall outcome by increasing the risk of complications and increasing costs; however, our paper shows that the association of alloplastic reconstruction in patients with radiotherapy can be performed safely and with low costs in carefully selected patients. |
| first_indexed | 2024-03-11T08:57:58Z |
| format | Article |
| id | doaj.art-7a1bacee65014876b9cbaa682817b88a |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-11T08:57:58Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-7a1bacee65014876b9cbaa682817b88a2023-11-16T19:58:00ZengMDPI AGCurrent Oncology1198-00521718-77292023-02-013021916192310.3390/curroncol30020149Outcomes and Economic Evaluation in Delayed Two-Stage Breast Reconstruction in Romania: The Influence of RadiotherapyAndrei Ludovic Porosnicu0Stefania Mihaela Riza1Ioana Antonia Stanculescu2Sorin Viorel Parasca3Cristian Radu Jecan4Ruxandra Diana Sinescu5Department of Plastic Surgery and Reconstructive Microsurgery, Elias Emergency University Hospital, 011461 Bucharest, RomaniaDepartment of Plastic Surgery and Reconstructive Microsurgery, Elias Emergency University Hospital, 011461 Bucharest, RomaniaDepartment of Plastic Surgery and Reconstructive Microsurgery, Elias Emergency University Hospital, 011461 Bucharest, RomaniaDepartment of Plastic Surgery and Reconstructive Microsurgery, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Plastic Surgery and Reconstructive Microsurgery, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Plastic Surgery and Reconstructive Microsurgery, Elias Emergency University Hospital, 011461 Bucharest, RomaniaThe current paper is a retrospective cohort study conducted on sixty-seven patients who underwent two-stage breast reconstruction over a 5-year period (2015–2020). Forty-one (61.2%) patients received radiotherapy (RT group), and twenty-six (38.8%) did not (non-RT group). Data regarding patients, oncological therapies, type of reconstruction, time of hospitalization, complications, and costs were collected. The statistical analysis was performed using IBM SPSS Statistics 25. General complications were noted for 18 patients (43.9%) in the RT group and for 7 patients (26.9%) in the non-RT group. Major complications were observed only in the first group (five patients–12.2%). The mean time of hospitalization in the RT group was 14.83 days for patients with complications versus 9.83 days for those without complications and 15.5 days versus 8.63 days, respectively, in the non-RT group. The mean cost for patients without complications was 235.64 euros, whereas the cost for patients with complications was 330.24 euros (<i>p</i> = 0.001). Radiation therapy can affect the overall outcome by increasing the risk of complications and increasing costs; however, our paper shows that the association of alloplastic reconstruction in patients with radiotherapy can be performed safely and with low costs in carefully selected patients.https://www.mdpi.com/1718-7729/30/2/149breast cancerradiotherapybreast reconstructionalloplastic breast reconstructionautologous breast reconstructioncosts |
| spellingShingle | Andrei Ludovic Porosnicu Stefania Mihaela Riza Ioana Antonia Stanculescu Sorin Viorel Parasca Cristian Radu Jecan Ruxandra Diana Sinescu Outcomes and Economic Evaluation in Delayed Two-Stage Breast Reconstruction in Romania: The Influence of Radiotherapy Current Oncology breast cancer radiotherapy breast reconstruction alloplastic breast reconstruction autologous breast reconstruction costs |
| title | Outcomes and Economic Evaluation in Delayed Two-Stage Breast Reconstruction in Romania: The Influence of Radiotherapy |
| title_full | Outcomes and Economic Evaluation in Delayed Two-Stage Breast Reconstruction in Romania: The Influence of Radiotherapy |
| title_fullStr | Outcomes and Economic Evaluation in Delayed Two-Stage Breast Reconstruction in Romania: The Influence of Radiotherapy |
| title_full_unstemmed | Outcomes and Economic Evaluation in Delayed Two-Stage Breast Reconstruction in Romania: The Influence of Radiotherapy |
| title_short | Outcomes and Economic Evaluation in Delayed Two-Stage Breast Reconstruction in Romania: The Influence of Radiotherapy |
| title_sort | outcomes and economic evaluation in delayed two stage breast reconstruction in romania the influence of radiotherapy |
| topic | breast cancer radiotherapy breast reconstruction alloplastic breast reconstruction autologous breast reconstruction costs |
| url | https://www.mdpi.com/1718-7729/30/2/149 |
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