Persistent intraocular Ebola virus RNA is associated with severe uveitis in a convalescent rhesus monkey

Persistent intraocular Ebola virus RNA is associated with severe uveitis in a convalescent rhesus monkey

Deep characterization of uveitis in a rhesus monkey confirms Ebola virus RNA persistence is associated with severe immunopathology in the eye, with broader implications for the prevention and treatment of sight-threatening uveitis in human survivors of Ebola virus.

Bibliographic Details
Main Authors: Gabriella Worwa, Timothy K. Cooper, Steven Yeh, Jessica G. Shantha, Amanda M. W. Hischak, Sarah E. Klim, Russell Byrum, Jonathan R. Kurtz, Scott M. Anthony, Nina M. Aiosa, Danny Ragland, Ji Hyun Lee, Marisa St. Claire, Carl Davis, Rafi Ahmed, Michael R. Holbrook, Jens H. Kuhn, Erica Ollmann Saphire, Ian Crozier
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04158-2

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